B8-071 Treatment of Male Sexual Disorders Flashcards

1
Q

testosterone deficiency is defined as 2 morning levels less than […] ng + symptoms

A

300

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

inability to consistently achieve and maintain a satisfactory erection for sexual activity

A

erectile dysfunction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

why is it important to identify underlying comorbid conditions in ED patients?

A

high correlation of underlying CVD/diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is the mechanism of PDE5 inhibitors?

A

increase cGMP –> NO –> smooth muscle relaxation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

-afils

A

PDE5 inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

major contraindication to PDE5 inhibitors

A

nitrates for chest pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

men with ED and TD have better benefit when a PDE5i is combined with […]

A

testosterone therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

ED med that bypasses the nerves

also can be used in patients that fear injections

A

MUSE (alporatadil)

urethral suppository

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

persistent erection lasting 4 or more hours

A

priapism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

which type of priapism is more dangerous?

A

low flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

[high vs low flow priapism]

painful
glans is soft

A

low flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

[high vs low flow priapism]

caused by sickle cell disease

A

low flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

[high vs low flow priapism]

can be caused by trazadone, cocaine, and prazosin

A

low flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

[high vs low flow priapism]

can be caused by incorrect use of intracavernosal agents

A

low flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

treatment for low flow priapism

A

irrigation & distal shunts

(no proximal shunts)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

[high vs low flow priapism]
cause tissue death/necrosis

A

low flow

17
Q

[high vs low flow priapism]

non-painful
glans full

A

high flow

18
Q

[high vs low flow priapism]

caused by trauma resulting in AV fistula

A

high flow

19
Q

high vs low blood flow priapism can be determined via what test?

A

ABG

20
Q

treatment of high flow priapism

A

embolization

21
Q

when using VED, patients should not wear the ring greater than […] min

A

30 min

22
Q

bleeding/clotting disorders are a contraindication to what ED treatment?

A

VED

23
Q

acquired penile deformity due to fibrosis

A

peyronie’s disease

24
Q

most common cause of delayed ejaculation

A

SSRIs

(followed by neurologic diseases)

25
Q

common causes of premature ejaculation

A

anxiety, ED, TD, thyroid

26
Q

common causes of aspermia

A

DM, autonomic dysfunction, previous surgery

27
Q

“lack of sex drive” refers to

A

libido

28
Q

the most common disorders affecting libido include disturbances in [3]

A

testosterone levels
pysch disorders
hormone disorders

29
Q

physiologically, an erection is the result of increased […] and decreased […] to the penis

A

physiologically, an erection is the result of increased [blood flow] and decreased [outflow] to the penis

30
Q

[…] stimulation results in ejaculation and detumescence

A

sympathetic

31
Q

MOA of PDE 5i

A

inhibit cGMP breakdown

results in increased NO/decreased calcium –>smooth muscle relaxation –> increased blood flow via vasodilation

32
Q

which PDE 5i has the longest half-life?

A

tadalafil

33
Q

[…] is the best test to determine high flow priapism vs. low flow

A

penile blood flow

34
Q

a blood gas with a pO2 below […] is diagnostic of low flow priapism

A

40

35
Q

erection is a function of the […] nervous system

A

parasympathetic

Point, squeeze, shoot

36
Q

erection: NO leads to the increase of [….], allowing for smooth muscle relaxation

A

cGMP

37
Q

NE leads to the increase of […], allowing for smooth muscle contraction –> antierectlice

A

intracellular Ca++

38
Q

emission is a function of the […] nervous system

A

sympathetic

Point, squeeze, shoot

39
Q

MOA of PDE 5i

A

decrease breakdown of cGMP