Chapter 15 Flashcards
1
Q
Humoral Immunity
A
- Eliminates extracelluar pathogens
- mediated by B cells
- mature in bone marrow
- can make memory cells
2
Q
Cellular mediated immunity
A
- eliminates intracellular pathogens
-mediated by t cells - ## mature in thymus
3
Q
Lymphocyte receptors
A
- recognize specfic antigens
- BCR made by B cells
- TCR cant find free antigens alone need APC
4
Q
Lymphatic system,
A
- tissues and organs used to bring B cells and T cells to antigen
- Primary are bone marrow and thymus
5
Q
Antigens
A
- Anythings that elicits immune response
- Epitope- part of antigen recognized by immune system
- APC: B cells, dendrites, and macrophages
6
Q
Antibody
A
- FC region that is contant
- Fab region is variable
7
Q
Clonal Selection
A
B cells bound to Ag is activated and divided
8
Q
T cells
A
- Have many TCR
- Ag presented on MHC
9
Q
MHC class I
A
- Found on all nucleated cells
- Bind endogenous antigen
10
Q
MHC class II
A
- Found on APC only
- Binds to exogenous antigens
11
Q
Cytotoxic T cell
A
- Recognize MHC I
- kills cells
12
Q
Helper T cell
A
- Recognize MHC II
- Activates APC
- necessary for immune response
13
Q
Negative selection
A
T cells that react to self antigen anergy
14
Q
Positive selction
A
T cells multiply and form clones
15
Q
Naive lymphocyte pool
A
T cells that have not yet encountered foreign antigens
