Cell Membrane, Membrane Transport, and Membrane Potential 4 Flashcards

1
Q

How of the body is water?

A

60% of body weight in kg

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2
Q

What percentage of the body’s weight in kg is in the extracellular fluid?

A

20%
-5% blood plasma
-15% interstitial fluid

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3
Q

What percentage of the body’s weight in kg is in the interstitial fluid?

A

40%

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4
Q

What is the osmolarity difference between the extracellular and intercellular space?

A

none
-the osmolarity is equal inside the cells and outside of the cells most of the time
300 Osm

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5
Q

What is active transport?

A

the movement of something across the cell membrane the requires the input of energy

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6
Q

What are the two types of active transport?

A
  1. active transport with membrane proteins
  2. bulk (vesicular) transport
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7
Q

What are active transporter?

A

transmembrane proteins that move ions and hydrophilic building blocks across the plasma membrane against the concentration gradient

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8
Q

What are active transporters classified by?

A
  1. number of substances being transported
  2. direction substances are being transported
  3. source of energy for transport
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9
Q

What are active transporters that only move one substance across the membrane?

A

uniporter

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10
Q

What are active transporters that move more than one substance in the same direction across the membrane?

A

symporter

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11
Q

What are active transporters that move more than one substance in opposite directions across the membrane?

A

antiporter

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12
Q

What is primary active transport?

A

when the energy needed to move the substance against the concentration gradient comes directly from the breakdown of ATP

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13
Q

What is secondary active transport?

A

when the energy needed to move substance against the concentration gradient comes from one substance moving down its gradient is used to move a second substance against its concentration gradient

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14
Q

What is an example of a primary active transporter?

A

ATPase pumps
(Na-K pump)

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15
Q

What are the functions of the Na-K pump?

A

-maintain Na and K concentration differences
-establish negative membrane potential

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16
Q

How does the Na-K pump create a negative membrane potential?

A

3 positive sodiums are leaving the cell for every 2 positive K entering the cell
-more positive leaving than entering

17
Q

What is an example of a symporter?

A

Na/Glucose symporter
-Na move down gradient
-glucose move against gradient

18
Q

What is an example of an antiporter?

A

Na/Ca exchanger
-Na move down gradient
-Ca move against gradient

19
Q

What is vesicular transport?

A

move large substances across the plasma membrane

20
Q

What are characteristics of vesicular transport?

A

-gradient independent
-requires energy

21
Q

What is Endocytosis?

A

process of bringing something large into the cell
-forms vesicle
-removes a part of the cell membrane

22
Q

What is exocytosis?

A

process of bringing something large out of the cell
-vesicles fuse to membrane
-adds membrane to the plasma membraneH

23
Q

How does vesicular transport alter the plasma membrane?

A

endocytosis removes a portion of the membrane
-could remove receptors, proteins, sugars, and many other
exocytosis add to the membrane
-could bring receptors, fats, steroids

24
Q

What is pinocytosis?

A

form of endocytosis
-nonspecific drinking
-nonspecific substances brought into the cell

25
Q

What is phagocytosis?

A

endocytosis that only phagocytes do
-foreign substance brought into the cell
-part of the immune system

26
Q

What is receptor mediated endocytosis?

A

happens in all cells all the time
-ligands bind to specific receptors and specific substances brought into the cell

27
Q

What separates the plasma and interstitial fluid?

A

capillary wall