15. Intro to endocrinology Flashcards

1
Q

Where is atrial natriuretic peptide secreted from?

A

heart

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2
Q

function of ANP?

A

stimulates kidney to excrete for Na+ = decreased BV volume and pressure

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3
Q

which organ and cells secrete renin?

A

kidney - juxtaglomerular cells

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4
Q

function of renin

A

stimulates adrenal cortex to secrete aldosterone

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5
Q

5 basic categories of hormones

A
  1. modified AA
  2. polypeptides
  3. glycoproteins
  4. steriods
  5. fatty acid derivatives
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6
Q

what time of hormone is insulin

A

polypeptide

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7
Q

what time of hormone is testosterone

A

steriod

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8
Q

what time of hormone is prostaglandin

A

FA derivatives - eicosanoids

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9
Q

what time of hormone is FSH

A

glycoprotein

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10
Q

what time of hormone is epinephrine

A

Modified AA

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11
Q

2 hormones secreted by posterior pituitary

A
  1. oxytocin

2. ADH

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12
Q

which cells secrete ADH?

A

supraoptic nuclei

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13
Q

which cells secrete oxytocin?

A

paraventricular nuclei

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14
Q

which cells secrete GH?

A

somatotropes

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15
Q

function of ACTH

A

stimulate Adrenal medulla to produce NE and E

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16
Q

cause of goitre

A

thyroid receptor Ab = hypothyroidism

17
Q

4 functions of T4

A
  1. protein synthesis
  2. bone growth
  3. neuronal maturation
  4. cell differentiation
18
Q

function of calcitonin - and 2 ways how

A

reduce Ca2+ by bone resorption and increasing Ca2+ secretion via kidney

19
Q

function of PTH

A

increase Ca2+

20
Q

2 hormones secreted by thymus ?

A

thymopoietin

thymosin

21
Q

function of thymopoietin

A

stimulates production of T cells

22
Q

is the pancrease exocrine or endocrine

23
Q

what do delta cells of islets of langerhans secrete?

A

somatostain

24
Q

2 functions of somatostatin

A
  1. inhibit release of glucagon + insulin

2. slows food absorption

25
in which organ and which cells are NE and E secreted?
adrenal medulla - spherical chromaffin cells
26
3 hormone srelease by adrenal cortex
1. cortisol 2. aldosterone 3. androgens
27
precursor for testosterone and oestrogen
dehydroepi-androsterone
28
2 hormones secreted by ovary
progesterone and oestrogen
29
what is gigantism caused by ?
increased GH in childhood
30
what is acromegaly caused by?
increased GH in adulthood
31
what is pituitary dwarfs caused by?
decreased GH in childhood
32
cause of hyperthyroidism - graves disease?
autoimmune
33
what is cretism caused by?
hypothyroidism in childhood
34
what is endemic goitre caused by?
hypothyroidism resulting from insufficient iodine
35
what is myxedema caused by?
hypothyroidism in adults - autoimmune
36
what is addisons disease caused by?
hyposecretion of cortisol + aldosterone