Biological - Holzel Flashcards

1
Q

What is the background of the study

A
  • mindfulness: practise of purposely bringing ones attention to the present moment experience without evaluation
  • Goal of mindfulness is to wake up inner workings of our mental, emotional, physical processes
  • Helps reduce stress + anxiety
  • Studies comparing individuals practising different forms of meditation reveal differences in grey matter in various brain areas linked to meditation
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2
Q

What is the aim of the study?

A
  • To investigate the potential long term effect of a mindfulness based stress reduction programme on brain grey matter density
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3
Q

Describe the sample

A
  • ppts recruited from ppl enrolled in MBSR (mindfulness based stress reduction) programme
  • Uni of Massachusetts USA
  • Enrolled to help w stress levels either choosen to attend / referred by doctor
  • physically / psychologically healthy
  • Right handed
  • No meditation classes in past 6 months
  • max of 4 classes in last 5 years
  • 10 in lifetime
  • 22-55 yrs old (mean age of 38yrs)
  • ppt who completed study given discounted MBSR course fee
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4
Q

Describe the experimental group

A
  • 6 males
  • 10 females
  • mean age of 38 years
  • 13 caucasians
  • 1 asian
  • 1 african american
  • 1 multi ethnic
  • Average of 17.7 yrs of education
  • (SD = 1.9)
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5
Q

Describe the control group

A
  • 11 males
  • 6 females
  • mean age of 39 yrs
    -13 caucasians
  • 2 asian
  • 1 hispanic
  • 2 african american
  • Average of 17.3yrs of education
  • (SD = 1.8)
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6
Q

Describe the research methodology

A
  • study is an experiment > researchers looking for causal relationship between MBSR + grey matter conc in brain structure
  • some measurements taken in controlled setting (MRI scans) but other parts in natrual setting (MBSR exercises preformed by ppts)
  • main part was experiment > one part was correlation as researchers wanted to know if relationship between amount of time spent on mindfulness exercises + increase in grey matter
  • LONGITUDINAL design as data collected over period of 8 weeks
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7
Q

What was the IV

A
  • whether ppts recieved MBSR / or not
  • if recieved meditation or not
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8
Q

What is the DV

A
  • Grey matter conc in specific brain structures
  • Time spent on mindfulness exercises between weekly sessions which was recorded in daily diary
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9
Q

Describe the FFMQ

A
  • Five Facet Mindfulness Questionnaire
  • Self report
  • 39 ques scale
  1. Observing
  2. Describing
  3. Acting with awareness
  4. Non judging of inner experience
  5. Non reactivity to inner experience

5 point likert scale

Negative statements are reversed on the scale

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10
Q

What the timings for the procedure

A
  • MBSR program was 8 weekly group meetings for 2 and half hours
  • Plus one full day 6.5hrs on 5th week of course
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11
Q

What were the 3 parts of the MBSR programme?

A
  1. BODY SCAN: slowly becoming aware of sensations in each area of body in turn gradually developing awareness of whole body / mind
  2. MINDFUL YOGA: gentle / stretching, co-ordinated, slow movements and breathing w a focus on moment to moment experience
  3. SITTING MEDITATION: awareness of sensation of breathing + sensory information (sight, smell, touch, taste)
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12
Q

Describe the sitting meditation

A
  • ppts recieved audio recordings
  • 45 min guided mindfulness exercises
  • Instructed to practise daily at home
  • Facilitate minfulness into daily life taught to practise mindfulness in everyday activities such as eating, walking, washing dishes
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13
Q

What are the details for scanning

A
  • ppts scanned at Martinos Center for biomedical imaging
  • Charlestown MA
  • Scanned 2 weeks before + after
  • Control scanned 2x
  • Approx 2 months apart
  • Average time of 56.25 days (SD: 4.5 days) in between scanning sessions for the MBSR grp
  • Average time of 65.67 days (SD: 11.22 days) between scanning sessions for the control grp
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14
Q

Data for formal homework exercises

A
  • Mean: 22.6hrs
  • SD: 6.3hrs
  • Average: 27 mins day
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15
Q

Data for body scan practise

A
  • Mean: 699 mins
  • SD: 217 min
  • Range: 103 - 775 min
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16
Q

Data for mindful yoga

A
  • Mean: 327 min
  • SD: 194 min
  • Range: 103 - 775 min
17
Q

Data for sitting meditation

A

Mean: 332 mins
SD: 211 min
Range: 0 - 775 min

18
Q

Describe the changes in mindfulness scores between 2 groups

A
  • ppts in MBSR grp significantly increased their mindfulness scores in
    1. Awareness
    2. Observing
    3. Non judging
  • When change compared to that of control grp (not expected to change) changes in mindfulness scores of MBSR grp were significantly greater on all 3 subscales
19
Q

Describe details from the pre test stage?

A
  • Grey matter conc tested in left hippocampus were no differences detected between MBSR + control grp at the start of the study
  • No changes in grey matter conc in control grp between the 2 test points
20
Q

What are the locations that had grey matter changes for the MBSR group?

A

MBSR grp experienced significant increase in grey matter conc in the following areas:

  1. Left hippocampus
  2. Posterior cingulate cortex
  3. Temporo parietal junction
  4. Cerebellum
21
Q

What are the results from the study

A
  • changes in cerebellum observed in 2 locations > included brainstem
  • 2 grps showed no significant difference in grey matter conc in these structures before MBSR training > appears differences at 8 weeks due to MBSR + not pre exisiting individual differences
  • No correlation between changes in these 4 areas + amount of hw completed by the ppt
  • Time spent on mindfulness less important than regularity of practise
  • Brain regions are involved in learning, memory, emotion regulation, perspective taking
22
Q

What are the 4 conclusions from the study?

A
  1. Hypothesised increases in grey matter conc within left hippocampus were confirmed
  2. Adult nervous system has capacity for plasticity and the structure of the brain can change in response to training
  3. Study demonstrates longitudinal changes in brain gray matter conc following 8 week MBSR course compared to the control grp
  4. Whole brain analyses identified significant increases in grey matter conc in
    posterior cingulate cortex
    Temporo parietal junction
    Cerebellum