Lymphocytes Flashcards

1
Q

What is another word for wbc

A

Leukocytes

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2
Q

What immune cells are innate

A
  • macrophages
  • granulocytes
  • dendritic cells
  • nk cells
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3
Q

What immune cells are adaptive

A
  • b cells
  • T cells
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4
Q

What are the three innate immune responses

A

Fast, non specific and generic

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5
Q

What innate body surface défenses do we have

A

Skin, hairs, one way urine flow

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6
Q

How does adaptive immunity work

A

It is antigen specific

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7
Q

What do the b cells do

A

Humoral immunity- relating to body fluid

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8
Q

What do T cells do

A

Cell mediated immunity- killing

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9
Q

What is the nucleus like of a lymphocyte

A

Large and relatively round that fills the cytoplasm

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10
Q

How big are lymphocytes

A

1.5 - 3.5 x 10^9/L

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11
Q

What is the life span of lymphocytes

A

Many years

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12
Q

What is the function of lymphocytes

A

Central role in the immune system as it divides into b and T cells

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13
Q

How big are neutrophils

A

2.5 - 7.5 x 10^9/L

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14
Q

How big are monocytes

A

0.2 - 0.8 x 10^9/L

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15
Q

How big are eosinophils

A

0.04 - 0.44 x 10^9/L

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16
Q

How big are basophils

A

0.01 - 0.1 x 10^9/ L

17
Q

What are the surface layer proteins called

A

MCH - major histocompatibility complex

18
Q

What encodes MCHs in humans

A

HLA human leukocyte antigen

19
Q

What are the three populations of lymphocytes

A

Natural killer, b cells, T cells

20
Q

Where are T cells made

A

The thymus

21
Q

Where are MCH-1 found

A

On the surface of all nucleated cells

22
Q

Where are MCH-11 found

A

On the surface of antigen presenting cells

23
Q

What are the two types of T cells

A

Helper and cytotoxic

24
Q

What MCH do cytotoxic cells recognise

A

MCH-1

25
Q

What MCH do helper cells recognise

A

MCH-11

26
Q

How to T cells kill

A

Apoptosis. Cell lysis by creating pores

27
Q

What do t helper cells do

A

Help other immune cells become fully functional

28
Q

Where are b cells made

A

Bone marrow

29
Q

What are the role of b cells

A

Mount a specific immune response by producing antigen specific antibiotics

30
Q

How do b cells recognise antigens

A

B cell receptor

31
Q

What is the role of plasma cells

A

The production and secretion of an antigen specific antibody

32
Q

What characteristics do plasma cells have

A
  • extensive RER and Golgi apparatus
  • lower levels of membrane bound antibodies
33
Q

What do memory b cells do

A

Ensure a quick secondary response