Bovine Infertility & Pregnancy Wastage Flashcards

1
Q

What is the pregnancy risk/rate? Why can they be especially low at certain farms?

A

function of service risk (detecting estrus) and conception risk (breeding) over 21 days

misinterpretation of estrus signs

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2
Q

How is conception rate calculated? How does it compare in beef and dairy cattle with pregnancy exams at days 26 and 45?

A

(females pregnancy at exam)/(females inseminated) x 100 = %

  • DAY 26 - beef = 70%; dairy = 40% (higher in heifers)
  • DAY 45 - beef = 65%; dairy = 30-40% (higher in heifers)
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3
Q

What is the difference between embryonic death, abortion, stillbirth, and neonatal loss?

A

death before the fetal period within 42 days (75% of pregnancy waste!)

death of fetus prior to age of viability

death of fetus in utero that would have been viable extra uterine

death of newborn

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4
Q

What are 5 causes of anestrus without a corpus luteum?

A
  1. ovarian agenesis/aplasia
  2. Freemartin - heifer twin to bull, resulting in a chimera
  3. post-partum anestrus
  4. cystic ovarian disease
  5. post-partum complications
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5
Q

What are 3 post-partum complications associated with anestrus without a CL?

A
  1. metritic delays
  2. retained fetal membranes
  3. ketosis
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6
Q

What cattle has a genetic predisposition for developing ovarian agenesis/aplasia

A

Danish Red cattle —> no ovaries

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7
Q

What is a Freemartin heifer?

A

chimera twin of a male resulting from placental vascular anastomoses by 30 days of gestation, where anti-mullerian hormone, testosterone, and male-derived hematopoietic progenitors flow from the male to the female twin

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8
Q

What are 5 typical phenotypes of Freemartin heifers?

A
  1. normal to small vulva
  2. increased anogenital distance
  3. enlarged clitoris
  4. prominent tuft of hair @ ventral commissure
  5. varying degrees of internal development
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9
Q

How is a Freemartin heifer diagnosed?

A
  • history of heterosexual multiple birth
  • palpation/vaginal probe (short tract)
  • PCR
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10
Q

What is postpartum anestrus? What are the most common causes in beef and dairy cattle?

A

no cycling following the 60-day voluntary waiting period taken to avoid high metabolic imbalances and healing of the reproductive tract

  • BEEF = rarely separated from calf, which is continually suckling = negative energy balance
  • DAIRY = poor nutrition, continual milking = negative energy balance
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11
Q

What is cystic ovarian disease? What are the 2 classifications?

A

presence of follicle(s) with a diameter of at least 20 mm at one or both ovaries in the absence of active luteal tissue —> interferes with normal ovarian cyclicity

  1. FOLLICULAR = estrogen secretion, nymphomania
  2. LUTEAL = progesterone secreted
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12
Q

In what cattle is cystic ovarian disease most common? When is it especially seen?

A

dairy cattle

  • interval between calving and first service
  • interval between calving and conception
  • increases with parity
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13
Q

What causes the development of cysts seen in cystic ovarian disease?

A

absence of a preovulatory surge due to a functinal breakdown in the positive estradiol feedback loop

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14
Q

Cystic ovarian cysts, pathogenesis:

A
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15
Q

What are the 4 major options for treating cystic ovarian disease?

A
  1. GnRH, hCG - induces other follicles to become dominant and ovulate
  2. PGF2α
  3. synchronization protocols
  4. progesterone (CIDR)

cysts unable to ovulate!

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16
Q

What are 3 causes of anestrus with a CL?

A
  1. pregnancy
  2. unobserved estrus or apparent estrus - silent het, no display of estrus
  3. failure of prostaglandin release
17
Q

How does the CL lifespan compare with intact and missing uterus?

A
  • INTACT = 15-17 days, normal cycle
  • TOTAL UTERECTOMY = 148 days, normal gestation length
  • PARTIAL UTERECTOMY = 15-17 day normal cycle if CL is present on the intact side; 35 days if CL is on the missing side due to countercurrent exchange taking longer to take effect
18
Q

What are 4 causes of failure of prostaglandin release?

A
  1. uterus unicornis - variable estrus length
  2. segmental aplasia
  3. hydrometra, pyometra, mucometra
  4. mummification - requires CL, can look like anestrus

causes anestrus with CL

19
Q

What are 6 causes of a cow cycling without getting pregnant?

A
  1. heat stress
  2. poor timing of AI
  3. mechanical
  4. uterine didelphys - 2 cervices, uterine horns not connected
  5. paraovarian cysts
  6. male issues
20
Q

What is a mechanical cause of a cycling cow that is not getting pregnant?

A

segmental aplasia - “white heifer syndrome” in white Shorthorns + uterus unicorns, imperforated hymen

single recessive sex-linked gene that causes an arrest in the development of the Mullerian duct —> if ovulation occurs on the missing side, there is nowhere for the sperm to meet for insemination

21
Q

What chromosoma abnormality causes bovine infertility?

A

1:29 Robertsonian translocation

22
Q

What are some fatal fetal anomalies?

A
  • arthrogryposis multiplex (curly calf syndrome)
  • complex vertebral malformation
  • pulmonary hypoplasia with anasarca
  • brachyspina syndrome
  • neurogenic hydrocephalus
23
Q

What are some toxic plants/toxins that can cause bovine infertility?

A
  • nitrate: nitrite, methemoglobin, hypoxia
  • estrogenic plants
  • Ponderosa pine
  • lupines, hemlock, locoweed, tree tobacco
  • mycotoxins: aflatoxin, DON (more common in swine)
24
Q

What causes infectious infertility? 2 most common causative agents?

A

true bovine venereal disease, most common in beef cattle, since they most commonly perform natural mating rather than AI

  1. Tritrichomonas foetus
  2. Campylobacter fetus subsp. venerealis

(most commonly asymptomatic in bulls)

25
Q

How do bulls and cows present with Tritrichomonas foetus infection?

A

BULLS = typically asymptomatic +/- mild balanoposthitis localized in the prepuce and distal urethra

COW = loss of conceptus (15-80 days), inflammation of the reproductive tract, post-coital pyometra, extended calving syndrome, irregular estrous cycles

26
Q

How do older bulls contribute to the spread of Tritrichomonas foetus? Younger bulls?

A

chronic carries > 4 y/o

spontaneous clearance < 3 y/o

27
Q

How does inflammation of the reproductive tract in cows with Tritrichomonas foetus progress?

A
  • vaginitis
  • cervicitis
  • endometritis
  • salpingitis
28
Q

How are bulls tested for Tritrichomonas foetus?

A
  • clip hair from sheath
  • flush preputial pouch with saline
  • connect syringe to a guarded pipet and insert it into the sheath until the tip of close to the fornix
  • apply negative pressure on pipet and scrape it against the penis and prepuce
  • remove pipet and place collected smegma into the InPouch TF travel media
29
Q

What 2 treatments are recommended for Campylobacter fetus subsp. venerealis infection?

A

vibriosis

  1. dihydrostreptomycin
  2. slaughter
30
Q

What are 2 other common subspecies of Campylobacter fetus? How do they compare to subspecies venerealis?

A
  1. fetus
  2. jejuni
  • not venereally transmitted
  • incidental, opportunistic
  • mostly affect sheep
31
Q

Causes of bovine infertility:

A
32
Q

What should be submitted for histopathology in cases of abortion?

A

abortus AND fetal membranes

  • lesions can be found on placenta!