Lecture 18 Flashcards

1
Q

What is a holobiont?

A

An organism and its associated microbiome

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2
Q

What are the roles of the gut microbiota?

A

immuno-modulation
protection against pathogens
nutrient aquisition

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3
Q

How can drugs influence the gut microbiota?

A
  1. Transformation of drugs -> make them toxic
  2. Shut down metabolism
  3. Reduces drug effect
  4. Retargeting of initial drug target to new target
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