NSAIDs

Question 1

Inflammation

Answer 1

Occurs upon infections or noxious stimuli
Eliminates harmful agents (microbes, toxins) and necrotic cells
Initiates the healing process
May injure normal tissues
Too strong response
Prolonged response
Inappropriate

Question 2

inflammation signs

Answer 2

Heat
Redness
Swelling
Pain
Loss of function

Question 3

Chemical mediators of inflammation

Answer 3

Vasoactive amines
Eicosanoids
PAF
Cytokines TNF IL-1 chemokines -> acute inflammation
Interferon-y (IFN-y) -> chronic inflammation
Complements components
C3a and C5a
Coagulation and kinin systems
Bradykinin, thrombin, fibrinopeptide s