2.4 the nucleus

Question 1

What is a transcription factor?

Answer 1

A protein that targets a specific gene regulatory sequence that is important in the control of transcription.

Question 2

Which transcription factor, important in prostate cancers, moves into the nucleus to activate gene expression?

Answer 2

The androgen receptor (AR).

Question 3

Nuclear pore complexes

Answer 3

Large multiprotein structures that span the nuclear membrane and regulate entry and exit of materials into and from the nuclear compartment.

Question 4

Excitable cells

Answer 4

Cells in which stimulation leads to depolarisation of the membrane, causing an action potential. Examples are neurons, myocytes and pancreatic b cells.