Renal Function Test Flashcards

1
Q

The standard tests used to measure the filtering capacity of the glomeruli

A

Clearance test

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2
Q

Stability of substance in urine during 24- hour urine collection

A

Clearance test

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3
Q

Clearance test Reported in

A

mL/min

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4
Q

STANDARD METHOD for GFR

A

Urea clearance test

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5
Q

Demonstrate progression of renal
disease or response to therapy

A

Urea clearance test

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6
Q

REFERENCE METHOD for GFR

A

Inulin clearance test

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7
Q

Not routinely done because of the necessity for
continuous IV infusion

A

Inulin clearance test

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8
Q

Inulin clearance test PRIMING DOSE:

A

25ml of 10% inulin solution

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9
Q

Inulin clearance test CONTINUOUS INFUSION:

A

500ml of 1.5% inulin solution

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10
Q

Inulin clearance test
REFERENCE VALUES: male

A

127 ml/min

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11
Q

Inulin clearance test
REFERENCE VALUES: female

A

118 ml/min

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12
Q

Most commonly used; screening method of GFR

A

Creatinine clearance

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13
Q

waste product of muscle metabolism

A

Creatinine clearance test

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14
Q

Creatinine clearance
REFERENCE VALUES: Male
◦ 75- 112 mL/ min  Female

A

85-125 mL/ min

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15
Q

Creatinine clearance
REFERENCE VALUES: Female

A

75- 112 mL/ min

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16
Q

Standard body surface

A

1.73 m2

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17
Q

Creatinine clearance MINUTES

A

1440 mins

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18
Q

Indirect estimate of GFR

A

Cystatin C

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19
Q

Completely reabsorbed by the PCT, hence its
presence in urine denotes damage to the
tubules

A

Cystatin C

20
Q

good procedure for screening and monitoring
GFR.

A

Cystatin C

21
Q

Cystatin C specimen

A

Serum or plasma (not fasting)

22
Q

Cystatin C increase level

A

Acute and chronic renal failure

23
Q

Cystatin C method

A

Immunoassay

24
Q

Dissociates from human leukocyte antigens
at constant rate and is rapidly removed
from the plasma by glomerular filtration.

A

Beta 2 microglobulin

25
Q

A rise has been shown to be more sensitive
indicator of decrease in GFR than
creatinine clearance

A

Beta 2 microglobulin

26
Q

Not reliable in patients who have history of
immunologic disorders.

A

Beta 2 microglobulin

27
Q

Beta 2 microglobulin method

A

Enzyme immunoassay

28
Q

monitor patients already diagnosed with renal disease or at
risk for renal disease.

A

Estimated glomerular filtration rate

29
Q

the formulas are valuable when medications that require
adequate renal clearance need to be prescribed

A

Estimated glomerular filtration rate

30
Q

Stages of Chronic Kidney Disease : Kidney Damage with Normal
or high GFR
GFR:

A

> 90

31
Q

Stages of Chronic Kidney Disease : Kidney Damage with Mild decrease
GFR
Gfr:

A

60- 89

32
Q

Stages of Chronic Kidney Disease : Moderate decrease GFR

Gfr:

A

30-59

33
Q

Stages of Chronic Kidney Disease: Severe decrease GFR
Gfr:

A

15-29

34
Q

Stages of Chronic Kidney Disease : Kidney Failure
Gfr:

A

<15 - dialysis

35
Q

Ability of the tubules to reabsorb the essential
salts and water that have been nonselectively
filtered by glomerulus

A

Concentration test

36
Q

specific gravity of urine before entering
the renal tubules, will vary when the urine
enters the renal tubules for the reabsorption
process.

A

1.010

37
Q

Patients were deprived of fluids for 24 hours prior to
measuring specific gravity

A

Fishberg test

38
Q

Compare the volume and specific gravity of urine of
day and night urine samples

A

Mosenthal test

39
Q

specific gravity is influenced by the
number and density (molecular weight)
of the particles.

A

Osmolality

40
Q

FREEZING POINT OSMOMETERS
Principle:

A

Freezing point depression

41
Q

Temperature at which water and ice are in
equilibrium and is related to solute
concentration

A

Freezing point

42
Q

Freezing point osmometer standard reference:

A

Sodium chloride

43
Q

VAPOR PRESSURE OSMOMETERS
Principle:

A

Measure dew point

44
Q

VAPOR PRESSURE OSMOMETERS
Standard reference

A

Sodium chloride

45
Q

VAPOR PRESSURE OSMOMETERS
Standard reference

A

Sodium chloride

46
Q

test most commonly associated with tubular
secretion and renal blood flow

A

P-aminohippuric acid test

47
Q

The inability to produce an acid urine
in the presence of
metabolic acidosis

A

Renal tubular acidosis