quiz 7 Flashcards

1
Q

what are the 4 dietary lipids?

A

TAG
FSV
Cholesterol and CEs
phospholipids (PL)

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2
Q

describe TAG digestion in the stomach

A

TAG clumps together in the stomach and the exterior is digested by gastric lipase.
it removes one FA to create DAG.

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3
Q

describe TAG digestion in the small intestine

A

cck is secreted when chyme enters
the pancrease releases pancreatic lipase and colipase, which acts on the gallbladder to secrete bile

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4
Q

what are the lipids broken down into

A

emulsification droplets

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5
Q

describe emulsification droplets

A

lipids make up the center and bile salts make up the exterior

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6
Q

what binds to the droplet? why

A

pancreatic colipase, so lipase can access the lipids

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7
Q

what does pancreatic lipase remove

A

2 FAs from TAG and 1 FA from DAG

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8
Q

what is the end product of TAG digestion

A

MAGs and FAs, which need to get absorbed

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9
Q

what do droplets become after absorption

A

bile salts micelles

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10
Q

how are the products of digestion transported to the ER

A

fatty acid binding proteins

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11
Q

define reesterification

A

fatty acids recombining with MAGs

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12
Q

describe chylomicrons

A

what TAGs are packaged in
help with lipid transport

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13
Q

where do lipids first enter after the small intestine?

A

the lymphatic system

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14
Q

what are TAGs broken down to in the ruminant

A

1 glycerol and 3 FAs

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15
Q

what is glycerol converted to

A

VFAs

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16
Q

why is too much fat a problem

A

it can be toxic to animals

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17
Q

why are PUFAs more toxic

A

they contain double bonds

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18
Q

define bihydrogenation

A

removes double bonds in PUFAs

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19
Q

FAs can/can not cross the brush border

A

can

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20
Q

can lipid transport freely occur?

A

no

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21
Q

describe very low density lipoproteins

A

instead of going to the lymphatic system, it goes to the liver

22
Q

what makes up density

A

lipid:protein

23
Q

define apolipoproteins

A

proteins associated with lipoproteins

24
Q

what are the functions of lipoproteins

A

structural, cofactor for enzymes, and/or ligands for receptors

25
Q

what does apoB100 do

A

acts as a ligand

26
Q

what does apoE do

A

acts as a structure and cofactor

27
Q

what does apoC2 do

A

acts as a cofactor

28
Q

what does chylomicron contain

A

apoB48

29
Q

what does chylomicron react with in the bloodstream

A

apoC2

30
Q

what does chylomicron do

A

binds to enzymes in the capillary walls and releases lipids

31
Q

what is chylomicron a cofactor for

A

lipoprotein lipase

32
Q

what are lipoprotein lipases broken down into

A

glycerol and FAs

33
Q

where does glycerol go

A

the liver

34
Q

where do FAs go

A

into tissue for energy or storage

35
Q

what happens when 80% of the TAGs are released

A

apoC2 dissociates from chylomicrons

36
Q

define chylomicron remnant

A

what remains when apoC2 dissociates from chylomicrons

37
Q

when does chylomicron remnant get removed from the bloodstream

A

when apoB48 binds to the receptor on liver cells

38
Q

what do VLDLs use

A

apoB100 and apoE

39
Q

what do VLDLs associate with in the bloodstream

A

apoC2

40
Q

how many TAGs are initially released with VLDLs

A

50%

41
Q

what is created when apoC2 is dissociated from VLDL

A

intermediate density lipoprotein

42
Q

what do IDLs become

A

LDLs

43
Q

what does LDL transfer

A

cholesterol from the liver into the body

44
Q

what do LDLs use for transferring

A

apoB100

45
Q

describe the LDL steps

A

travels through the bloodstream
binds to apoB100 on capillary walls
cholesterol is diffused into tissues

46
Q

how long to LDLs stay in circulation

A

2 days

47
Q

where do LDLs go when cholesterol is absorbed

A

back to the liver

48
Q

what do HDLs do

A

the reverse of cholesterol transport: transport cholesterol from tissue using apoA1

49
Q

what are the steps of HDLs

A

binds to apoA1 receptors on capillary walls
cholesterol is desorbed from tissue
returns to liver with cholesterol

50
Q

what are the 4 roles of lipid metabolism

A

energy source
structural components
lubricants
signaling molecules

51
Q

what are the only two places that synthesize fat

A

adipose tissue and the liver