Immunology

Question 1

symptoms of IgE mediated reaction

Answer 1

itchiness
angio edema
colicky abdo pain
sneezing
SOB

Question 2

non IgE mediated reactions

Answer 2

eczema
reflux
infantile colic
diarrhoea
constipation

Question 3

what Ix to do for IgE mediated reactions

Answer 3

skin prick test

Question 4

what Ix to do for non-IgE mediated

Answer 4

this causes a delayed reaction so an elimination diet can be tried

Question 5

4 ways to classify immunodeficiecny

Answer 5

T cell
B cell
complement
neutrophil

Question 6

T cell immunodeficiency, common presentation and causes

Answer 6

opportunistic infections e.g. pneumocystis jirovecii

SCID, ataxia telangiectasia, HIV

Question 7

B cell immunodeficiency
common presentation and causes

Answer 7

sinopulmonary infections / bronchiectasis
common variable immunodeficiency

Question 8

neutrophil immunodeficiency
common presentation and causes

Answer 8

skin abscess (bacterial/fungal)

chronic granulomatous disease

Question 9

complement immunodeficiency
common presentation and
causes

Answer 9

frequent Neisseria infection

hereditary angioedema
SLE

Question 10

dose of adrenaline for anaphylaxis

Answer 10

0.5ml of 1:1000 IM

Question 11

C1 deficiency

Answer 11

increased risk of bacterial infections of Resp and Gastro. Increased risk of SLE

Question 12

C2 deficiency

Answer 12

increased risk of Resp and urogenital infections

Question 13

C4 deficiency

Answer 13

increased risk of resp and skin infections, SLE and vasculitis

Question 14

C5, 6, 7, 8, 9 deficiency

Answer 14

increased risk of neisseria meningitidis and neisseria gonorrhoe