ulcerative colitis Flashcards

1
Q

where does ulcerative colitis affect?

A
  • colon only
  • starts at rectum- sigmoid- proximal colon
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2
Q

does ulcerative colitis go through wall?

A

no
remains in mucosa
- doesn’t go through wall

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3
Q

does ulcerative colitis have skip lesions?

A

NO
- its continuous

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4
Q

does UC have granulomatous tissue?

A

NO

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5
Q

what are the goblet cells like in UC?

A

depleted

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6
Q

describe the crypt abscesses in UC

A

increased

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7
Q

how is UC diagnosed?

A
  1. pANCA positive
  2. colonoscopy
  3. biopsy
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8
Q

what would a UC colonoscopy show?

A
  • continuous leadpipe sign
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9
Q

what would a biopsy for UC show?

A
  • mucosal inflammation with crypt hyperplasia
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10
Q

how do you determine the severity of flare?

A
  • truelove and witts scoring
  • mild/mod/severe
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11
Q

what are the symptoms for UC?

A
  • LLQ pain
  • Tenesmus - rectal infection pain
  • Diarrhoea with blood, water and mucus
  • extra intestinal symptoms
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12
Q

what are the extra intestinal symptoms for UC?

A
  • Uveitis/ episcleritis
  • erythema nodosum
  • spondylarthropathy
  • PSC- Primary sclerosis cholangitis
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13
Q

what are the complications of UC?

A
  • toxic megacolon
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14
Q

what are the risk factors of UC?

A

NSAIDS
stress
jewish
smoking protects!!!!

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15
Q

how is UC treated for flares?

A

sulfasazine + prednisolone

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16
Q

how is UC treated for remission?

A

azathioprine, methotrexate, lidosporin

17
Q

how is UC treated with biologics?

A

anti TNF alpha - infliximab

18
Q

what are the 4 ways UC is treated ?

A
  1. flares
  2. remission
  3. biologics
  4. surgery- CURATIVE
19
Q
A