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helicobacter pylori Flashcards

1
Q

define H. pylori

A

-a bacteria that affects your stomach
- less virulence commensals in GI tract
- gram negative

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2
Q

what is the pathophysiology behind H pylori

A
  1. ↓ Somatostatin
  2. increase luminal gastric acid
  3. Urease -> results in ammonia generation
  4. ↓ HCO3- Secretion
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3
Q

what are the causes of H pylori ?

A

Peptic Ulcer disease
Gastritis
Gastric carcinomas
Unclean food
By mouth

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4
Q

how is H pylori diagnosed?

A
  • biopsy
  • stool antigen
    — C urea breath test
    ( both would be +ve)
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5
Q

how is H pylori treated?

A

tripple cap therapy
- clarithromycin, amoxicillin, PPI ( proton pump inhibitor)

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GI (20 decks)

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