13- The anatomy of the liver Flashcards
What is the function of the glissons capsule
Connective tissue that surrounds the liver.
How many surfaces do hepatocytes have
2 basal surfaces on opposite ends of the cell and each surface faces the blood
Where in the hepatocyte is bile secreted from
Bile is secreted from the apical surface around the hepatocytes middle
What connects neighbouring hepatocytes
The lateral surface
What is the arrangement of hepatocytes and what are they separated by
They are arranged into cords separated by vascular sinusoids
What vessels take blood to the liver
Hepatic artery and portal vein
What vessels take processed blood
Hepatic Veins
Where does blood mix in the liver and where does it drain
Mixes in the sinusoids and drains in the central vein
What is a sinusoid and how do they achieve their function
A small blood vessel found in the liver that functions similarly to a capillary
They have increased permeability compared to capillaries and allow larger molecules to leave the blood stream
What allows the passage of large molecules out of sinusoids
endothelial layer contains large intracellular gaps.
a further leak is allowed by fenestrations that penetrate endothelial cells.
What is different about the basement membrane in sinusoids
They are absent or discontinuous
Where does blood enter sinusoids
Enters via the portal vein and hepatic artery
What is the space called between endothelium and hepatocytes
Space of Disse
Where does the space of disse drain to
Drain into lymph nodes
What are the function of kupffer cells
Of the macrophage lineage found in the sinusoid
They are phagocytic and important in removing particulate material, including bacteria from portal blood
