HEMOGLOBIN Flashcards

1
Q

OCCURS WHEN HEMOGLOBIN BREAKS DOWN IN THE BLOD AND FREE HEMOGLOBIN RELEASED INTO PLASMA

A

INTRAVASCULAR HEMOLYSIS

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2
Q

OCCURS WHEN SENESCENT/OLD RBC ARE PHAGOCYTIZED BY MACROPHAGES IN THE LIVER OR SPLEEN.

A

EXTRAVASCULAR HEMOLYSIS

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3
Q

MEASURES THE AMOUNT OF FE +3 BOUND TO TRANSFERRIN

A

SERUM IRON

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4
Q

MEASURE THET TOTAL AMOUNT OF IRON THAT TRANSFERRIN CAN BIND WHEN FULLY SATURATED

A

TIBC

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5
Q

INDIRECT MEASUREMENT OF STORAGE IRON IN TISSUE AND BONE MARROW

A

SERUM FERRITIN

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6
Q

Hgb F CONTAINS

A

TWO ALPHA 2. GAMMA GLOBIN CHAIN

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7
Q

A COMPENSATIRY HGB AND CAN BE INCREASED IN HOMOZYGOUS HEMOGLOBINOPATHIES AND BETA THALLASEMIA MAJOR.

A

HGB F

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8
Q

HGB A CONTAINS

A

2 ALPHA
2 BETA GLOBULIN CHAIN

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9
Q

HGB A2 CONTAINS

A

2 ALPHA 2 DELTA GLOBIN CHAIN

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10
Q

HEMOGLOBIN FE 2+ and O2 seen in arterial circulation

A

Oxyhemoglobin

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11
Q

Hemoglobin Fe 2+ and no O2 seen in venous circulation

A

Deoxyhemoglobin

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12
Q

Hemoglobin Fe 2+ and carbon monoxide that has 200x more affinity for CP than O2

A

Carboxyhemoglobin

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13
Q

Hemoglobin with S cannot transport O2 and seldom reaches fatal levels

A

Sulfhemoglobin

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14
Q

Hemoglobin with FE 3+ cannot transport O2

A

Methemoglobin

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15
Q

choose Left shift or right shift
Decrease oxygen affinity and body pH
Increased O2 release, 2,3 BPG and body temp

A

RIGHT SHIFT

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16
Q

choose Left shift or right shift

decreased O2 release, 2,3 BPG and body temp
Increased oxygen affinity and body pH

A

LEFT SHIFT