Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

HEMATOLOGY 1 > erythrpocyte > Flashcards

erythrpocyte Flashcards

1
Q

aerobically converts glucose to pentose and produces NADPH

A

hexose mnophosphate shunt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

most common enzyme deficiency in the pentose phosphate pathway

A

G6PD DEFICIENCY

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

RECOMMENDED SCREENING TEST FOR G6PD DEFICIENCY

A

G6PD FLUORESCENT SPOT TEST

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

A SCREENING TEST FOR 6G6D DEFICIENCY WHERE THE PATTERN IS SLIGHTLY TO MODERATE INCREASED BUT IS PARTIALLY CORRECTED BY GLUCOSE

A

AUTOHEMOLYSIS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

CLAASIFICATION OF G6PD SEVERELY DEFICIENT
CLINICAL MANIFESTATION: HNSHA
VARIANTS: G6PD - SERRES AND G6PD MADRID

A

CLASS 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

CLAASIFICATION OF G6PD SEVERELY DEFICIENT
CLINICAL MANIFESTATION ASSOCIATED WITH FAVA BEANS AND FAVISM AND AY REQUIRED TRANSFUSION DURING HEMOLYTIC EPISODES
VARIANTS G6PD: MEDITERRANEAN
G6PD: CHATAM

A

CLASS 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

CLAASIFICATION OF G6PD MODERATELY TO MILDLY DEFICIENT
CLINICAL MANIFESTATION: SELF LIMITED, EPISODIC
VARIANTS:G6PD A AND G6PD CANTON

A

CLASS 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

CLAASIFICATION OF G6PD MILDLY DEFICIENT
CLINICAL MANIFESTATION NONE
VARIANTS: G6PD B AND G6PD A THAT MAY ALSO MANIFEST CLASS 3

A

CLASS 4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

CLAASIFICATION OF G6PD INCREASED ACTIVITY
CLINICAL MANIFESTATION NONE
VARIANTS NONE

A

CLASS 5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

MAINTAINS IRON IN THE HEME IN ITS REDUCED STATE

A

METHEMOGLOBIN REDUCTASE PATHWAY

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

FOR THE PRODUCTION OF 2,3- BPG

A

RAPOPORT-LEIEBERING SHUNT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

THE CURVE WHEN THE 2 VARIABLES ( PARTIAL PRESSURE OF OXYGEN AND AFFINIY OF HB0 ARE PLOTTED ON TEH GRAPH

A

OXYGEN DISSOCIATION CURVE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

A SHIFT IN TEH CURVE DUE TO ALTERATION IN PH
EFFECT OF HYDROGEN INS AND CO2 ON TEH AFFINITY OF HEMOGLOBIN FOR OXYGEN

A

BOHR EFFECT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

DEPICTS THE OCCURRENCE BY WHICH THE BINDING OF O2 TO THE HB PROMOTES THE RELEASE OF CO2

A

HALDANE EFFECT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

SHIFT TO THE LEFT OR SHIFT TO THE RIGHT
INCREASED PH
DECREASED PCO2
DECREASED 2,3-BPG
DECREASED TEMPERATURE

A

SHIFT TO THE LEFT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

V SHIFT TO THE LEFT OR SHIFT TO THE RIGHT
INCREASED PH
DECREASED PCO2
DECREASED 2,3-BPG
DECREASED TEMPERATURE
WHAT IS THE AFFINITU?

A

INCREASED

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

SHIFT TO THE LEFT OR SHIFT TO THE RIGHT
DECREASED PH
INCREASED PCO2
INCREASED 2,3-BPG
INCREASED TEMPERATURE

A

SHIFT TO THE RIGHT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

SHIFT TO THE LEFT OR SHIFT TO THE RIGHT
DECREASED PH
INCREASED PCO2
INCREASED 2,3-BPG
INCREASED TEMPERATURE
WHAT IS THE AFFINITY

A

DECREASED

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

INCREASED NUMBER OF RED CELLS WITH VARIATION IN SIZE

A

ANISOCYTOSIS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

LARGER THAN NORMAL RBC.
USUALLY SEEN WHEN NCV IS GREATER THAN 100
ASSOCIATED WITH IMPAIRED DNA

A

MACROCYTES

21
Q

SMALLER THAN NORMAL
USUALLY SEEN WHEN THE MCV IS <80 FL
ASSOCIATED WITH DEFECTIVE HEMOGLOBIN FORMATION

A

MICROCYTES

22
Q

BLOOD CELL HISTOGRAM THE X AXIS IS FOR:

A

CELLS SIZE

23
Q

BLOOD CELL HISTOGRAM THE Y AXIS IS FOR

A

NUMBER OF CELLS

24
Q

TWO PARAMETERS CALCULATED FRIM RBC HISTOGRAM

A

MCV AND RDW

25
Q

IF THE RBC ARE MICROCYTES TE CURVE WILL SHIFT TO

A

RIGHT

26
Q

IF THE RBCS ARE MACROCYTIC THE CURVE WILL SHIFT. TO THE

A

LEFT

27
Q

IF THE HISTOGRAM CURVE IS BIMDAL THEN THERE ARE

A

TWO POPULATION OF RBC IN THE SAMPLE

28
Q

WHAT CAN CAUSE BIMODAL DISTRIBUTION

A

BLOOD TRANSFUSION
COLD AGGLUTINATION
HEMOLYTIC ANEMIA WITH SCHISTOCYTE PRESENT

29
Q

A CALCULATED INDEX GIVEN BY HEMATOLOGY ANALYZERS TO HELP IDENTIFY ANISOCYTOSIS AND PROVIDE INFORMATION ABOUT ITS DEGREE

A

RED CELL DISTRIBUTION WIDTH

30
Q

BASED IN BITH THE WIDTH OF THHE RBC DISTRIBUTION CURVE AND THE MEAN RBC SIZE
DEPENDENT BY WIDTH AND MCV

A

RDW-CV

31
Q

THE ACTUAL MEASUREMENT OF THE WIDTH OF THE RBC DISTRIBUTION CURVE IN FL
NOT INCLUENCED BY MCV

A

RDW SD

32
Q

BETTER AND MOST RELIABLE MEASURE OF RBC VARIABILITY SPECIFICALLY IN HIGH ABNORMAL CONDITIONS

A

RDW-SD

33
Q

WHEN WILL BE THE RDW DECREASE IN NEWBORNS

A

6 MOS OF AGE

34
Q

VARIATION IN THE NORMAL COLOR

A

ANISOCHROMIA

35
Q

OCCURRENCE OF HYPOCHROMIC CELLS AND NORMOCHROMIC CELLS IN THE BLOOD SMEAR

A

ANISOCHROMIA

36
Q

ANISOCHROMIA CAN BE SEEN IN

A

SIDEROBALSTIC ANEMIA
HYPOCHROMIA AFTER TRANSFUSION WITH NORMAL CELLS
WEEKS AFTER IRON THERAPY FOR IDA

37
Q

GRADING OF HYPOCHROMIA

A

1+ AREA OF CENTRAL PALLOR = 1/2 DIAMETER

2+ AREA OF CENTRAL PALLOR = 2/3

3+ AREA OF CENTRAL PALLOR = 3/4

4+ AREA OF CENTRAL PALLOR = THIN RIM OF HB

38
Q

BC WITH A THIN RIM OF HEMOGLOBIN AND A LARGE CLEAR CENTER

A

ANULOCYTE/ PESSARY CELL OR GHOST CELL

39
Q

ANULOCYTE MGHT BE SEEN IN

A

IRON DEFICIENCY ANEMAI

40
Q

BASICALLY THE ONLY DISEASE IN WHICH THE MCHC IS HIGH

A

HHEREDITARY SPHEROCYTOSIS

41
Q

HS HAS 3 KEY CLINCIAL MANIFESTATION

A

SPLEENOMEGALY
ANEMIA
JAUNDICE

42
Q

LAB RESULT OF PX WITH HS

A

DAT- NEGATIVE
MCV NORMAL TO LOW
MCH- NORMAL
MCHC SLIGHTLY INCREASED

43
Q

CONFIRMATORY TEST FOR HS DISEAE

A

EMA BINDING TEST

44
Q

LARGER THAN NORMAL RED CELL WITH BLUISH TINGE

A

PLOYCHROMATOPHILIC ERYTHROCYTES

45
Q

BLUISH TINGE IN POLYCHROMATOPHILIC ERYTHROCYTE IS CAUSED BY

A

THE PRESENCE OF RESIDUAL RNA

46
Q

LARGE UMBER OF POLYCHROMATOPHILIC ERYTHROCYTE CAN BE FOUND IN

A

DECREASED RBC SURVIVAL
HEMORRHAGE
ERYTHROID HYPERPLASTIC MARROW

47
Q

EARLIEST METHOD PROVIDED BY THE HEMATOOLOGY ANALYZER TO EMASURE RED CELL VARIATION

A

RDW-CV

48
Q

WHAT CONDITION HAS THIS DECREASED MCV AND LITTLE OR NO ANISOCYTOSIS

A

ANEMIA OF CHRONIC INFECTION

49
Q

WHAT CONDITION HAS THIS DECREASED MCV AND INCREASED ANISOCYTOSIS

A

IDA

HEMATOLOGY 1 (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions