monoclonal antibodies Flashcards
what is the first step to produce monoclonal antibodies?
mouse is injected with a specific pathogen/ antigen.
the mouses immune system responds
what is the second step to produce monoclonal antibodies?
specific white blood cells called lymphocytes produce antibodies
what is the third step to produce monoclonal antibodies?
tumor cells are able to replicate but can’t make antibodies
what is the fourth step to produce monoclonal antibodies?
lymphocytes are combined with tumour cells
what is the fifth step to produce monoclonal antibodies?
cells now called hybridoma and can make specific antibodies.
screened to make sure they are producing the right one
what is the sixth step to produce monoclonal antibodies?
hybridoma cells copy themselves and produce clones as they divide rapidly
why are they called monoclonal antibodies?
they are identical antibodies made from cloned cells
how does injecting monoclonal antibodies into a patient with a disease help?
the antibody binds on the antigen which makes the phagocytes engulf them
in an experiment why would some patients be given a placebo?
the compare the effects
what is a phagocyte
white blood cells which engulf and digest pathogens.
what is the purpose of a control stip in a pregnancy test?
to check it works
