Ketamine

Question 1

Ketamine Trade Name?

Answer 1

Ketalar

Question 2

Ketamine Classfication?

Answer 2

Dissociative anesthetic & analgesic

Question 3

Ketamine Mechanism?

Answer 3

As a non-competitive antagonist for NMDA and glutamate receptors, it blocks HCN1 channel receptors causing disassociation between cortical and limbic system.

Question 4

Ketamine Indications?

Answer 4

-Restraint
-Excited delirium
-Induction agent for RSI
-Pain management

Question 5

Ketamine Contraindications?

Answer 5

-Significant Hypertension

Question 6

Ketamine Side Effects/Precautions?

Answer 6

-Hallucination
-Hypertension
-Increased skeletal muscle tone
-Increased salivation
-Nausea/Vomiting
-Tachycardia
-Palpitations

Question 7

Ketamine Adult Dose?

Answer 7

RIPP - 4,2,1, 0.2/0.3
Restraint: 4mg/kg IM
Induction for RSI: 2 mg/kg IV/IO
Post Intubation: 1mg/kg every 5-15 min.
Pain management: 0.2mg/kg IV/IO 0.3mg/kg IM

Question 8

Ketamine Pediatric Dose?

Answer 8

RIP - 4,2,1, 0.2/0.3
Restraint: 4mg/kg IM
Induction for RSI: 2 mg/kg IV/IO
Post Intubation: 1mg/kg every 5-15 min.

Question 9

Ketamine Onset of Action?

Answer 9

30 seconds IV/IO; 3-4 minutes IM

Question 10

Ketamine Duration of Action?

Answer 10

5-10 minutes IV; 15-25 minutes IM

Question 11

Ketamine Max Dose Adult/Pediatric?

Answer 11

Restraint: 500mg single dose, 150mg addt’l in 5-10min
Pain management:
IV/IO 20mg/dose
IM: 30mg/dose

Question 12

Ketamine Routes of Administration?

Answer 12

IM/IV/IO Depending on curcumstance

Question 13

Ketamine How Supplied?

Answer 13

50mg/ml and 100mg/ml vials