Naloxone

Question 1

Naloxone Trade Name?

Answer 1

Narcan

Question 2

Naloxone Classification?

Answer 2

Opioid Antagonist

Question 3

Naloxone Mechanism?

Answer 3

Competitively binds to opiate receptors in the brain, displacing opiates and reversing effects of opiates

Question 4

Naloxone Indications?

Answer 4

Respiratory depression associated with opioid overdose

Question 5

Naloxone Contraindications?

Answer 5

None in an emergency setting

Question 6

Naloxone Side Effects/Precautions?

Answer 6

• Seizures
• Pulmonary edema
• Tachycardia
• Hypertension
• Nausea/vomiting
• Diaphoresis
• Dysrhythmia
• Cardiac arrest

Question 7

Naloxone Adult Dose?

Answer 7

0.4 - 2.0mg repeat at 5-minute intervals to a max of 10 mg

Question 8

Naloxone Pediatric Dose?

Answer 8

0.1 mg/kg (max 2 mg/dose); repeat at 5-minute intervals as needed

Question 9

Naloxone Onset of Action?

Answer 9

1-2 minutes

Question 10

Naloxone Duration of Action?

Answer 10

Variable: related to opiod concentration

Question 11

Naloxone Max Dose Adult/Pediatric?

Answer 11

Adult 10mg, Pediatric 2mg/dose

Question 12

Naloxone Routes of Administration?

Answer 12

IV/IO/IM/IN

Question 13

Naloxone How Supplied?

Answer 13

0.4mg/ml and 1mg/ml vials, ampules, and pre?lled syringes