Quesmed videos (Hodgkin's lymphoma)

Question 1

What are risk factors associated with hodgkin’s lymphoma?

Answer 1

HIV

Epstein-Barr virus

Autoimmune conditions, such as rheumatoid arthritis and sarcoidosis

Family history

Question 2

What cells do hodgkin’s lymphoma arise from?

Answer 2

Hodgkin’s lymphoma arises from the B-lymphocytes in the germinal cells of the lymphoid tissue.

Question 3

What cells are present on blood film for Hodgkin’s lymphoma?

Answer 3

Reed-sternberg cells (however absence of these cells does not exclude Hodgkin’s lymphoma as a potential diagnosis).

Question 4

Why are patients given a HIV test when suspected of Hodgkin’s lymphoma?

Answer 4

In patients with HIV, there is a 5-10x more risk of developing Hodgkin’s lymphoma.

Question 5

What are features of Hodgkin’s lymphoma?

Answer 5

Short history of enlarged mass (most likely lymphadenopathy)

Mostly painless

Can be painful after alcohol consumption

Question 6

What is Hodgkin’s lymphoma?

Answer 6

A malignant tumour of the lymphatic system that is characterised histologically by nucleated giant cells (Reed-sternberg cells).

Question 7

What is the typical age range affected by Hodgkin’s lymphoma?

Answer 7

Bimodal age peak

20-34 years old

AND

> 70 years old