obs and. gynae physio Flashcards

1
Q

what cells produce testosterone

A

Leydig cells

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2
Q

The Y chromosome so males contains what gene

A

SRY

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3
Q

what ducts forms male genitalia

A

Mesonephric (wolffian)

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4
Q

what gender has anti Mullerain hormone that degenerates the paramesonephric ducts

A

males

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5
Q

what ducts allow for the development of female genitals

A

paramesonephric

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6
Q

what leads to a bicornate uterus

A

fusion of the paramesonephric ducts

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7
Q

what cells form the blood testis barrier

A

sertoli cells

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8
Q

when sperm enter the female they undergo what

A

capacitation - removal of cholesterol and glycoproteins from the head of th esperm to allow it to bind to the zonal pellucida of the egg cell

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9
Q

what connective tissue cells can respond to LH and can secrete andorgens under its influence

A

theca folliculi

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10
Q

what cells form the zona pellucida

A

granulosa cells

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11
Q

consider follicles as secondary when

A

they have antrum (fluid filled space)

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12
Q

what stimulates Leydig cells in the testes to produce testosterone

A

Lh

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13
Q

what drives sperm production in sertoli cells

A

FSH

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14
Q

in females LH binds to what cells and that produces androgens

A

theca cells

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15
Q

in females FSH binds to what cells

A

granulosa cells - increase activins and inhibins (have positive and negatvie feedback on the pituitary)

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16
Q

when is the only time oestrogen positively feedback on LH and FSh

A

if there is high oestrogen levels

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17
Q

progesterone is released by what in females

A

corpus luteum

18
Q

what has an inhibitory effect on LH and FSH

A

progesteroen

19
Q

rise in LH causes what

A

increase in progesteron in females and increase in testosterone in males

20
Q

rise in FSH causes what

A

increase in oestrogen synthesis and oogenesis in females and onset of sperm production in males

21
Q

most common condition of hypergonadotrophic hypogonadism in males is

A

Klinefelters

22
Q

body temperature increases in what phase

A

luteal

23
Q

there is a peak of wha tin luteal phase

A

progesterone

24
Q

dysmenorrhoea refers to

A

painful periods

25
Q

menopause characterised by reduction of

A

circualting oestrogen

26
Q

although oestrogen decreases in menopause what increase significntly

A

levels of FSH and LH

27
Q

what protects bone mass

A

oestrogen

28
Q

oestrogen is protective against what

A

heart disease

29
Q

when is classed as early menopause

A

between 40-45

30
Q

pre eclampsia is due to failed or incomplete differentiation of what cells

A

cytotrophoblastic cells

31
Q

umbillical vein and arteroes are opposite ie

A

umbillical vein delivers oxygenated blood and umbillical arteries are used to transport deoxygenated blood

32
Q

ductus arteriosis bypasses the

A

lungs

33
Q

ductus venosus bypasses the

A

liver

34
Q

patent ductus arteriosus has a

A

continous machinery murmur

35
Q

widely split second heart sounds

A

patent foramen ovale

36
Q

acrosomal reaction involbes

A

release of enzymes that digest the zona pellucida

37
Q
A
38
Q

what is it called when the zona pellucida is digested and the sperm fuses with the cell membrane of the oocyet. this causes icnrease in calcium levels

A

cortical reaction

39
Q

what is responsble for iniitaing uterine contractions

A

oxytocin

40
Q

what T3 and T4 levels rise in pregnancy

A

total

41
Q

what leads to a decrease in blood pressure in the first and second trimester of pregnancy

A

progesterone