17 - 1

Question 1

Which drug is bactericidal?

Answer 1

Metronidazole

Question 2

Which drug is an antineoplastic?

Answer 2

Cytarabine

Question 3

Pulmonary fibrosis?

Answer 3

Bleomycin

Question 4

Cardiotoxicity?

Answer 4

Doxorubicin (Anthracyclines)

Question 5

Peripheral neuropathy side effect?

Answer 5

Vincristine (vinca alkaloid)

Question 6

MOA of vinca alkaloids?

Answer 6

Suppress microtubule polymerization

Question 7

What drug has beta-lactamase resistance due to clavulanic acid? Augmentin

Answer 7

Augmentin

Question 8

What bacteria is responsible for periodontal abscesses?

Answer 8

Bacteriodes

Question 9

Amoxicillin and augmentin are responsible for what side effect?

Answer 9

Diarrhea

Question 10

What antibiotic commonly causes overgrowth of clostridium difficile?

Answer 10

Clindamycin

Question 11

Which antibiotic commonly has drug-drug interactions?

Answer 11

Erythromycin??

Question 12

Which of the following is bactericidal?

Answer 12

Metronidazole

Question 13

Which of the following does not have a drug complication with Warfarin?

Answer 13

Amox (metron does)

Question 14

What systemic antibiotic would you use for an already immunosuppressed patient? ??

Answer 14

bactrim
or amox

Question 15

What drug is know to cause immunosuppression?

Answer 15

Methotrexate

Question 16

Why do we only prescribe Azithromycin for short periods of time?

Answer 16

Long half-life

Question 17

What causes tooth discoloration in children?

Answer 17

Doxocycline

Question 18

Which of the following drugs in condraindicated for use during pregnancy?

Answer 18

Doxocycline

Question 19

Which of the following has a mechanism of action that acts directly on ergosterol?

Answer 19

Nystatin

Question 20

Which would sufficiently treat against bacteria producing beta lactamase?

Answer 20

Amoxicillin +
Clavulanic acid

Question 21

Generalized aggressive periodontitis. What would be the most appropriate adjunctive ABX
regimen?

Answer 21

Amox + metronidazole

Question 22

What ABX best treats a purulent abscess?

Answer 22

TMP/SMX?? (clinda or augmentin?)

Question 23

Which of the following of the backbone of HAART?

Answer 23

NRTI (nucleoside reverse transcriptase
inhibitor)

Question 24

Which prohibits the assembly of new retroviral cells?

Answer 24

PI’s (protease inhibitors) “navirs-ritonavir)

Question 25

Antibiotic prophylaxis when?

Answer 25

Prosthetic heart valve

Question 26

What procedure would be consider high risk for infective endocarditis?

Answer 26

Manipulation of gingiva

Question 27

Which of the following is not a life-long infection?

Answer 27

Influenza A

Question 28

Which would be the treatment of influenza? Oseltamavir (Tamiflu)

Answer 28

Oseltamavir (Tamiflu)

Question 29

Which would be the acute treatment for cryptococcal mengingitis?

Answer 29

Amphotericin B

Question 30

What ABX would you use to treat an early odontogenic infection (<3 days)?

Answer 30

Penicillin

Question 31

MOA of fluconazole is what?

Answer 31

To prevent conversion of lanosterol to ergosterol

Question 32

Which drug causes periostitis after chronic use?

Answer 32

Voriconazole

Question 33

Adverse lipid effects?

Answer 33

Protease Inhibitors (PI’s)

Question 34

What agent should be used for an HIV patient when the CD4 count drops below 200?

Answer 34

Bactrim

Question 35

Ritonavir?

Answer 35

Is a protease inhibitor??

Question 36

What ABX acts on the bacterial cell wall?

Answer 36

Amoxicillin (penicillin, etc… Beta lactams)

Question 37

Which of the following scenarios suggests need for adjunctive systemic ABX in a patient with periodontal abscess?

Answer 37

Fever

Question 38

All patients with a reported heart condition should receive antibiotic prophylaxis prior to a dental procedure?

Answer 38

False

Question 39

What group of pathogens is most common for late odontogenic infections?

Answer 39

Strict anaerobes

Question 40

Which of the following most accurately described a bacterial sinus infection?

Answer 40

Purulent nasal drainage and facial pain with no improvement after 10 days

Question 41

The more time an antifungal agent remains in the mouth, the more effective the agent will be when treating oropharyngeal candidiasis?

Answer 41

True (because of time dependent)

Question 42

Which group of antiretrovirals is most likely to cause metabolic side effects?

Answer 42

PI’s (protease inhibitors)

Question 43

Which of the following options for oropharyngeal candidiasis has the highest cariogenic risk?

Answer 43

Nystatin

Question 44

What is the first step of Post Exposure Prophylaxis?

Answer 44

Cleanse

Question 45

Which of the following is an appropriate definition for Beta-Lactamase?

Answer 45

An enzyme released from a bacteria that has the potential to disable an antibiotic

Question 46

The cephalosporin class of antibiotics kills anaerobic bacteria?

Answer 46

False

Question 47

Metronidazole (Flagyl) eradicates anaerobic bacteria?

Answer 47

True

Question 48

Which of the following drugs acts directly on cell wall formation?

Answer 48

Amox

Question 49

Which of the following antibiotics is associated with tendon side effects?

Answer 49

Ciprofloxacin (fluoroquinolones)

Question 50

Which of the following is metabolized into a toxic metabolite that causes hemorrhagic cystitis?

Answer 50

Cyclophosphamide

Question 51

How do you alleviate the symptoms of the toxic metabolite acrolein?

Answer 51

MESNA

Question 52

Which of the following best describes how a mutated tumor suppressor gene may lead to the generation of cancer cells?

Answer 52

Inhibitory proteins may not function properly and inappropriate growth of cells remains unchecked

Question 53

Paclitaxel inhibits mitosis of cancer cells by

Answer 53

inhibiting disassembly of microtubulin (taxanes)

Question 54

Peripheral neuropathy is a notable side effect of which of the following antineoplastic agents?

Answer 54

Oxaliplatin and vincristine