18 - 1 Flashcards

1
Q

action of zolendronic acid:

A

either to block blood and nutrient to prevent
tumor growth, or to impair the synergistic effect between o-clasts and
resorption

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2
Q

Bavacizumab:

A

anti-angiogenesis

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3
Q

Oxaliplatin:

A

a platinum

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4
Q

Pain to cold:

A

Oxaliplatin

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5
Q

Cardiotoxic:

A

___-rubicin (anthracyclines= cytotoxic antibiotics)

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6
Q

Vincristine MOA:

A

prevent formation of mitotic spindles

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7
Q

Taking Cyclosporine tell drs because:

A

can cause immunosuppression and
DDI’s

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8
Q

Can cause immunosuppression:

A

Methotrexate

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9
Q

Prednisone inhibits pain by blocking:

A

prostaglandin production

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10
Q

Can give if patient is on SSRIs (for HSV-1):

A

Acyclovir

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11
Q

Backbone drug for HIV:

A

NRTIs

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12
Q

HIV drug that works by inhibiting assembly:

A

Protease Inhibitors

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13
Q

HIV drug that causes INC in TG, etc:

A

Protease inhibitors

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14
Q

Prophylaxis Abx given when CD4<100:

A

Bactrim wasn’t an option, so I put
Azithro

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15
Q

Virus that isn’t life long:

A

influenza

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16
Q

Best for patient with xerostomia and mild candidiasis:

A

nystatin

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17
Q

Lowest potential for DDI;s:

A

nystatin (I put fluconazole)

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18
Q

Azithromycin Qweek:

A

HIV

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19
Q

Azithromycin is only given once a day because:

A

has longer t ½

20
Q

HIV treatment therapy:

A

Genvoya

21
Q

Need ABx prophylaxis:

A

artificial heart valve

22
Q

Influenza treatment:

A

“antidine”s or Tamiflu?

23
Q

Fluconazole MOA:

A

prevent conversion of lanosterol into ergosterol

24
Q

Nystatin MOA:

A

binds to ergosterol

25
Q

Interact with Warfarin:

A

metronidazole, diflucan,????bactrim, cipro

26
Q

EARLY odontogenic infections are primarly:

A

either + aerobes or – aerobes

27
Q

Cluvandrate helps B-lactams against bacteria that produce:

A

B-lactamase

28
Q

Main cause of endocarditis:

A

Strep

29
Q

Active against + strep, -, and anerobes:

A

Augmentin

30
Q

Give for dental infection >3 days:

A

Clindamycin

31
Q

Most likely to cause oral abscess:

A

Bacteriodes?

32
Q

ADR of augmentin:

A

diarrhea

33
Q

Want to give if patient is immunocompromised:

A

Amoxil (because it is a CIDAL)

34
Q

B-lactamase works by:

A

hydrolizing penicillin

35
Q

Best anerboic coverage:

A

metronidazole

36
Q

Do not give cephalosporin if:

A

urticarial rash to pen

37
Q

Not okay for preganancy:

A

doxy

38
Q

Would need to add systemic abx:

A

fever

39
Q

Cancer:

A

rapid proliferation and undifferenitation

40
Q

Procedure that requires pre-med:

A

gingival manipulation

41
Q

Chemo patients:

A

stomatitis will likely occur within 1 week

42
Q

Can cause MRONJ:

A

not Tacrollimus

43
Q

Kill HSV-1:

A

none

44
Q

Block cell wall synthesis:

A

Pen (all B-lactams)

45
Q

C.diff:

A

Clindaymcin