20 - 1

Question 1

Zoledronate (Zometa) has what mechanism?

Answer 1

Inhibits osteoclasts from binding to the ruffled border

Question 2

Denosumab (Xgeva) has what mechanism?

Answer 2

Inhibits RANK from binding to RANKL

Question 3

A patient comes in sayng that they are receiving treatment for osteoporosis and also has
active periodontal disease. Which of the following is true?

Answer 3

The risk of ARONG is low and it is more beneficial to do dental treatment
possibly with antibiotic prophylaxis

Question 4

Bevacizumab

Answer 4

????????

Question 5

Cancer cells have what characteristics

Answer 5

Low differentiation, high proliferation

Question 6

Question about correct prescription. Make sure it has dose, name, how many times per
day, how to take it and how much bottle will contain

Answer 6

Question about correct prescription. Make sure it has dose, name, how many times per
day, how to take it and how much bottle will contain

Question 7

Question about how to dose a kid 37 lbs with amoxicillin 25kg/mg/day.

Answer 7

Answer was 150
mg/5 mL q8h

Question 8

Bevacizumab has what mechanism?

Answer 8

Stops VEG from binding to VEGF

Question 9

Which one of these is a monoclonal antibody?

Answer 9

Denosumab

Question 10

The drug is cisplatin. What type of drug is that?

Answer 10

Platinum compound

Question 11

Patient reports cold sensitivity and just started cancer treatment. What are they taking?

Answer 11

Oxaliplatin

Question 12

Which of the following does immunosuppression?

Answer 12

Methotrexate (other ones don’t do immunosuppression; ex: amoxicillin)

Question 13

Patient comes in and was told to tell you he is on cyclosporin. Which of the following
isn’t true?

a. He has gingival hyperplasia
b. He has high risk of infection
c. He will have issues with fluconazole
d. He is at risk for MRONJ

Answer 13

He is at risk for MRONJ

Question 14

Which of the following species is found in an abscess?

Answer 14

Bacteroides

Question 15

Bacterial infection has been around for >3 days. What do you give?

Answer 15

Augmentin

Question 16

If you’re using clauvulonic acid, it helps amoxicillin in bacteria that contain what?

Answer 16

Beta lactamases

Question 17

All of the following are beta lactams except
a. Penicillin
b. Amoxicillin
c. Cephalosporins
d. Azithromycin

Answer 17

?????

Question 18

All of these could cause MRONJ excpt what
a. Denosumab
200
b. Zolendronic acid
c. Bevacizumab
d. Tracrolimus

Answer 18

Tracrolimus

Question 19

Highest drug interactoins is seen with

Answer 19

Erthromycin

Question 20

Viridans Strep has the highest resistance to
a. Amoxicillin
b. Clindamycin
c. Azithromycin

Answer 20

Azithromycin

Question 21

Patient is immunosuppressed. What do you give them?

Answer 21

Amoxicillin

Question 22

Patient has HIV. What would you use to maintain them?

Answer 22

Combo with 4 drugs in it (listed all four)

Question 23

Why do you give amoxicillin three times a day?

Answer 23

It’s half life is 8 hours and it is time dependent

Question 24

What is the first organism seen in an early infection?

Answer 24

Gram + aerobe

Question 25

If a patient has this reaction to amoxicillin you will not give them cephalex

Answer 25

Blistering rash

Question 26

Which drug do you use for gram negatives, anaerobes and Bacteroides?

Answer 26

Augmentin

Question 27

What treats an anaerobic infection?

Answer 27

Metronidazole

Question 28

Which one is a drug reaction with warfarin?

Answer 28

Metronidazole

Question 29

Which drug is known to cause high risks of diarrhea?

Answer 29

Augmentin

Question 30

Which bacteria is known to cause C. diff?

Answer 30

Clindamycin

Question 31

What do you not give a pregnant person?

Answer 31

Doxycycline

Question 32

When would you give a person with infective endocarditis prophylaxis? a. Gingival manipulation b. Ortho movement c. Removable placement d. Radiographs

Answer 32

Gingival manipulation

Question 33

Which of the following heart conditions would be required to have infective carditis prophylaxis? a. Heart attack b. Prosthetic heart valve c. Heart failure

Answer 33

Prosthetic heart valve

Question 34

Antibiotics are indicated with

Answer 34

Systemic symptoms (fever)

Question 35

Which ones inhibits viral assembly?

Answer 35

Protein inhibitor

Question 36

Which of the following is not a life long disease?

Answer 36

Influenza A

Question 37

Which of the following has increased lipid accumulation and fat distrubtion?

Answer 37

Protease inhibitor

Question 38

What is the backbone of HAART?

Answer 38

NRTI

Question 39

What drug do you give someone who is immunosuppressed?

Answer 39

Amoxicillin

Question 40

CD4 count is below 50, what would you give them?

Answer 40

Azithromycin

Question 41

A patient takes azithromycin once a week. What disease do they have? a. HSV-1 b. HSV-2 c. HIV

Answer 41

HIV

Question 42

What drug lessens the effects of influenza?

Answer 42

Tamiflu

Question 43

What is the role of an azole?

Answer 43

Blocks enzyme from lanosterol to ergosterol

Question 44

How does Zometa work with breast cancer?

Answer 44

Symbiotic relationship that further decreases bone destruction

Question 45

Which drug is used for patient that has xerostomia and mild oral candida?

Answer 45

Nystatin

Question 46

Nystatin has what role?

Answer 46

Binds to ergosterol in cell membrane

Question 47

Which of the following has drug interactions with Warfarin? a. Tamiflu b. Amoxicillin c. Fluconazole

Answer 47

?????????????

Question 48

What is a side effect of methotrexate?

Answer 48

Oral mucositis