37 - Coma Flashcards

1
Q

Define hypersomnia

A

excessive sleepy but normal congnition on awakening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Define coma

A

eyes remain closed even after vigorous stimulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Define obtundation

A

mental blunting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

define abulia

A

awake but apathetic (lobotomized)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

define akinetic mutism

A

silent, alert, seemingly immobile. No mental activity with vigorous stimulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Define vegetative state

A

no awareness or meaningful interaction with environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What lesion of the midbrain would cause insomnia? Narcolepsy?

A

rostral midbrain lesions cause insomnia

caudal midbrain lesions cause narcolepsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the function of the reticular gray concerning coma?

A

important for arousal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Will a lesion of the upper pons cause coma if the midbrain and thalmus are fine?

A

yes. upper pons lesions can cause coma even without thalamic or midbrain injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is primary sleep initiator? How?

A

VLPO. deploys GABA to inhibit wake centers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How can you differentiate metabolic and structural comas by looking at the pupils?

A

pupil reflex is last to go in metabolic coma, but FIRST to go in structural

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

If a coma patient has elevated vital signs: structural or psychogenic coma?

A

structural elevates vitals.

Psychologic has normal vitals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is first sign of both central and transtentoral herniation?

A

Cheyne stokes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What causes the flexor response (decorticate)?

A

response to pain due to loss of corticol control of brainstem motor centers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What causes extensor (decerebrate) posturing?

A

response that arises after loss of the red nucleus and rubrospinal tract in midbrain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is perfect score on glasgow?

A
  1. above 12 is a good prognosis
17
Q

What parts of the brain mediate consciousness?

A
Arousal = ascending arousal system of rostral brainstem
Content = corticol circuits
18
Q

How can you distinguish structural from metabolic comas?

A

metabolic: non-focal signs (lateralizing signs like hemiparesis absent)
head CT negative
pupils STAY reactive even as brainstem functions lost.
Asterixes, multifocal myoclonus/tremor, uremia, liver failure, hypoxia
Stupor and coma reversible.

19
Q

What is immediate treatment for coma patients?

A

stabilize vitals (ABCs)
stabilize neck
determine history
empiracal D50, thiamine naloxone (opiate OD)

20
Q

What are the two componenets of consciousness?

A

arousal (sleep-wake cycels) and content (awareness)

21
Q

What is the most common coma causing lesion?

A

paramedian tegmental area lesions, just ventral to aqueduct of Sylvius

22
Q

What are signs of a central herniation?

A

reduced consciousness, small reactive pupils, decorticate psoturing (flexor), cheyne-stokes respirations, eventual midbrain failure

23
Q

What are sources of endogenous toxins for metabolic encephalopathy?

A

uremia and hepatic failure