Signaling Pathways of Endocrine Hormones

Question 1

cAMP

Answer 1

• FLAT CHAMP

- FSH, LH, ACTH, TSH, CRH, hCG, ADH (V2 receptor), MSH, PTH, calcitonin, GHRH, glucagon

Question 2

cGMP

Answer 2

• vasodilators

- ANP, NO (EDRF)

Question 3

IP3

Answer 3

• GOAT HAG

- GnRH, Oxytocin, ADH (V1 receptor), TRH, Histamine (H1 receptor), Angiotensin II, Gastrin

Question 4

Steroid receptor

Answer 4

• VETTT CAP

- Vitamin D, Estrogen, Testosterone, T3/T4, Cortisol, Aldosterone, Progesterone

Question 5

Intrinsic tyrosine kinase

Answer 5

• MAP kinase pathway - think growth factors

- insulin, IGF-1, FGF, PDGF, EGF

Question 6

receptor associated tyrosine kinase

Answer 6

• JAK-STAT pathway - think acidophiles and cytokines (PIG)

- Prolactin, Immunomodulators (e.g. cytokines- IL-2, IL-6, IL-8, IFN), GH