Adrenergic drugs

Question 1

What varies based on site of action and effects on receptor type

Answer 1

Therapeutic uses for adrenergic compounds

Question 2

What are the 2 names of adernergic drugs which stimulate the SNS

Answer 2

adernergic agonist or sympathomimetics

Question 3

What are the SNS neurotransmitters (catecholamines)

Answer 3

norepinephrine and epinephrine from the adrenal medulla and dopamine

Question 4

What two systems make up the ANS and provide checks and balance

Answer 4

SNS (fight/flight) and PNS (relax/digest)

Question 5

What are adrenergic receptor sites

Answer 5

places where drugs bind to produce effect they are located throughout the body for NE and Epinephrine catecholamines

Question 6

What are the 2 categories of adrenergic receptors

Answer 6

alpha and beta

Question 7

Alpha 1 receptors are located where

Answer 7

postsynaptic effector cells the nerve stimulates (one after)

Question 8

Alpha 2 receptors are located where

Answer 8

presynaptic nerve terminals release neurotransmitters (2 before)

Question 9

What is the dominant alpha adrenergic response

Answer 9

vasoconstriction and CNS stimulation. Alpha-constrictor

Question 10

Tony of P90X says eat apples 2 before and 1 after a workout. Say What?

Answer 10

Alpha 2 are presynaptic, Alpha 1 are postsynaptic

Question 11

All beta adrenergic receptors are located

Answer 11

postsynaptic effector cells

Question 12

Beta 1 are located where

Answer 12

Heart (1love) and kidney

Question 13

Beta 2 are located on smooth muscles fibers of

Answer 13

bronchioles, arterioles and visceral organs like uterus (oxytocin)

Question 14

Beta adrenergic drugs AGONIST relaxes my

Answer 14

lungs, stomach and womb but it stimulates my heart and cause glycogenolysis

Question 15

Alpha 2 and Beta 1 has the same effect in the

Answer 15

liver (glycogenolysis) and stomach (decrease motility)

Question 16

Beta 1 in the kidney does…

Answer 16

increase renin, volume and ultimately blood pressure

Question 17

Alpha 1 causes what in the eye

Answer 17

mydriasis

Question 18

The dopamine adernergic receptors causes dilation to

Answer 18

renal, mesenteric, coronary and cerebral arteries to and thereby increase blood flow to the tissues. Dope dilates at MCRC.

Question 19

The 2 enzymes responsible for stopping the catecholamine actions are MAO and COMT

Answer 19

MAO (pre) and COMT (synapse)

Question 20

What are the B1 effects the pancreas

Answer 20

decrease insulin release/increase glucose

Question 21

What receptors does the synthetic catecholamines stimulate

Answer 21

dobutamine (B1)

phenylephrine (A1)

Question 22

epinephrine stimulates what mostly

Answer 22

B1

Question 23

norepinephrine stimulates

Answer 23

A1

Question 24

Amphetamines are an example of indirect acting sympathomemetics which means it causes a

Answer 24

release of neurotransmitters from storage sites

Question 25

ephedrine are an example of a

Answer 25

mixed acting adernergic receptors

Question 26

B1 force, heart and conduction (otropic)

Answer 26

forcin’… heart/time…conduct/drama(dromo)

Question 27

Name 9 B2 bronchodilators are

Answer 27

albuterol and levalbuterol, ephedrine, epinephrine, formoterol,salmeterol, metaproterenol, pirbuterol and terbutaline

Question 28

I stop premature labor and act as a brondilator

Answer 28

terbutaline

Question 29

I am an alpha agonist used to treat mydriasis and open angle glaucoma

Answer 29

epinephrine and dipovefrin