19. Tumour Classification Flashcards Preview

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Flashcards in 19. Tumour Classification Deck (49)
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1
Q

Name 2 types of benign epithelial tumour

A
  • papilloma (SURFACE EPITHELIUM)

- adenoma (GLANDULAR EPITHELIUM)

2
Q

How are benign epithelial tumours further classified?

A
  • by cell type of origin eg. squamous cell (SURFACE)

- by name of glandular tissue of origin eg. colonic (GLANDULAR)

3
Q

What is the name of a benign tumour of squamous epithelium e.g. skin?

A

Squamous cell papilloma

4
Q

What is the name of a benign tumour of the ductal epithelium of the pancreas?

A

Pancreatic cystadenoma

5
Q

What are the exceptions to the normal rules of naming benign epithelial tumours?

A
  • melanoma
  • lymphoma
  • seminoma
  • mesothelioma
    etc
6
Q

What are malignant epithelial tumours called?

A

Carcinomas

7
Q

How are malignant epithelial tumours derived from surface epithelial named?

A

By prefixing carcinoma with the cell of origin eg. squamous cell carcinoma

8
Q

What is the name for malignant tumours derived from glandular/ductular epithelium?

A

Adenocarcinomas

9
Q

Name a benign tumour of stratified squamous epithelium eg. skin, oropharynx etc.

A

Squamous cell papilloma

10
Q

Name a bening tumour of basal cells of the skin

A

Basal cell papilloma

11
Q

Name a benign tumour of transitional epithelium of the bladder

A

Transitional cell papilloma

12
Q

Name a benign tumour of glandular epithelium of liver

A

Liver cell adenoma

13
Q

Name a benign tumour of glandular epithelium of thyroid

A

Follicular adenoma

14
Q

Name a malignant tumour of basal cells of the skin

A

Basal cell carcinoma

15
Q

Name a malignant tumour of glandular epithelium of colon

A

Colonic adenocarcinoma

16
Q

Name a malignant tumour of glandular epithelium of breast

A

Breast adenocarcinoma

17
Q

How are benign mesenchymal tumours named?

A
Prefix = tissue or cell of origin 
Suffix = '-oma'
18
Q

What is a benign tumour of bone?

A

Osteoma

19
Q

What is a benign tumour of adipose tissue?

A

Lipoma

20
Q

What is a benign tumour of smooth muscle?

A

Leiomyoma

21
Q

What is a benign tumour of skeletal muscle?

A

Rhabdomyoma

22
Q

What is a benign tumour of a blood vessel?

A

Angioma / haemangioma

23
Q

What is a benign tumour of cartilage?

A

Chondroma

24
Q

What is a benign tumour of fibrous tissue?

A

Fibroma

25
Q

What are malignant mesenchymal tumours called?

A

Sarcomas

26
Q

How are malignant mesenchymal tumours named?

A
Prefix = tissue or cell of origin
Suffix = '-sarcoma'
27
Q

What is a malignant tumour of adipose tissue?

A

Liposarcoma

28
Q

What is a malignant tumour of smooth muscle?

A

Leiomyosarcoma

29
Q

What is a malignant tumour of cartilage?

A

Chondrosarcoma

30
Q

What is a benign tumour of melanoyctes called?

A

Melanocytic nevus

31
Q

What is a malignant tumour of melanocytes called?

A

Melanoma

32
Q

Name 3 types of malignant tumour of blood cells

A
  • leukaemia
  • lymphoma
  • myeloma
33
Q

Name 5 types of CNS tumours

A
  • meningioma
  • astrocytoma
  • oligoendroglioma
  • ependymoma
  • medulloblastoma
34
Q

What is a meningioma?

A

Arises from meningeal tissue of brain (usually benign)

35
Q

What is an astrocytoma?

A

Arise from the star-shaped glial cells called astrocytes

36
Q

Name a type of astrocytoma

A

Glioblastoma multiforme (most common and most malignant of the glial tumours)

37
Q

What is an oligoendroglioma?

A

Originate from the oligodendrocytes of the brain or from a glial precursor cell

38
Q

What is an ependymoma?

A

Arises from the ependyma, a tissue of the central nervous system

39
Q

Where are germ cell tumours common?

A

Gonads

40
Q

How can germ cell tumours be divided?

A
  • seminomatous

- non-seminomatous

41
Q

Give an example of a seminomatous germ cell tumour

A

Seminoma

42
Q

Give an example of a non-seminomatous germ cell tumours

A

Teratoma (teeth/hair/muscle/neural/cartilage)

43
Q

What are the features of embryonal tumours?

A
  • occur in very young (under 5)

- have a histological resemblance to embryonic cells of that organ

44
Q

Give 4 examples of embryonal tumours

A
  • retinoblastoma (in eye)
  • nephroblastoma (Wilm’s tumour of kidney)
  • neuroblastoma (adrenal medulla or nerve ganglia)
  • hepatoblastoma (liver)
45
Q

What is a carcinosarcoma?

A

Malignant tumors that consist of a mixture of carcinoma (or epithelial cancer) and sarcoma (or mesenchymal/connective tissue cancer) eg. in ovaries

46
Q

Name 4 malignant tumours with benign names

A
  • melanoma
  • mesothelioma
  • myeloma
  • lymphoma
47
Q

What is a hamartoma?

A
  • non-neoplastic overgrowth of normal tissue
  • indigenous to the site of occurrence
  • developmental abnormalities
  • eg. lung hamartoma
48
Q

Hamartomas usually consist of what?

A

2 mature cell types normally found in the organ in which the lesion lies e.g. lung hamartoma = cartilage and bronchial epithelium

49
Q

What is a choristoma?

A
  • excess of normal tissue in an abnormal situation
  • nodules of organ parenchyma in another organ
  • aka. heterotropic rests
  • eg. normal (non-neoplastic) pancreas nodule in stomach