2. Acid-Base Flashcards
(40 cards)
pH
Hydrogen (indirect measurement of hydrogen ion concentration)
• the greater concentration of H ion more acidic and the lower the pH; less concentration more alkaline and the higher the pH
• anything 6.8-7.8 = no life
Reflection of the balance between carbonic acid and bicarbonate
carbonic acid: exhalable; results from aerobic metabolism of glucose (acid regulated by the lungs) and bicarbonate: nonexhalable; results from aerobic metabolism of fats and proteins and anaerobic metabolism of glucose (base regulated by the kidneys)
respiratory system acidosis
you increase respiratory rate (hyperventilation) you eliminate, “blow off,” CO2 (acid) therefore decreasing your CO2 acid—giving you ALKLAOSIS by reducing acid
respiratory system alkalosis
you decrease your respiratory rate (hypoventilation) you retain CO2 (acid) therefore increasing your CO2 (acid)—giving you ACIDOSIS by increasing acid load
Renal system acidosis
You have Acidosis when you have excess H+ and decreased HCO3- causing a decrease in pH. The Kidneys try to adjust for this by excreting H+ and retaining HCO3- base.
renal system alkalosis
You have Alkalosis when H+ decreases and you have excess (or increased) HCO3- base. The kidneys excrete HCO3- (base) and retain H+ to compensate. The respiratory system tries to compensate with hypoventilation to retain CO2 (acid)
pH normal*
7.35-7.45
pH decreased*
Acidosis
pH increased*
Alkalosis
pCO2 normal*
35-45
pCO2 decreased*
Alkalosis
pCO2 increased*
Acidosis
HCO3 normal*
22-26
HCO3 decreased*
Acidosis
HCO3 increased*
Alkalosis
pO2 normal*
80-100
pO2 decreased*
hypoxemia
pO2 increased*
O2 therapy
SaO2 normal*
85-100%
SaO2 decreased*
hypoxemia
metabolic acidosis
Decrease pH (lower than 7.35), decrease HCO3 (lower than 22) (If PaCO2 decreased then compensating)
metabolic acidosis caused by direct
direct loss of bicarb (too much acid, too little bicarb)
metabolic acidosis causes
increase H production(DKA, hyper-metabolism)
decrease H elimination (renal failure)
decrease HCO3 production (dehydration, liver failure)
increase HCO3 elimination (diarrhea, fistulas
metabolic acidosis s/s
o Associate with: diarrhea, diuretics, TPN, DKA, early renal insufficient, excessive chloride
o Symptoms: headache, drowsiness, pherial vasodilaiton especially pH below 7, drop in blood pressure, cold clammy, dysrythemia, shock