2. DNA Viruses

Question 1

DNA viruses that replicate in the nucleus

Answer 1

Adenoviruses
Herpesviruses
Parvoviruses

Question 2

DNA virus that replicates in the cytoplasm

Answer 2

Poxviruses

Question 3

The only single stranded DNA virus

Answer 3

Parvoviridae

Question 4

DNA virus associated with epidemics of keratoconjunctivitis

Answer 4

Adenovirus

Question 5

DNA virus that can cause cancer in animals

Answer 5

Adenovirus

Question 6

Disease caused by Hepadnavirus

Answer 6

Hepatitis B

Question 7

2 important antigens of Hepadnaviruses

Answer 7

Surface Ag

Core Ag

Question 8

Chronic hepatitis infection due to Hepadnavirus can lead to

Answer 8

Cirrhosis

Hepatocellular carcinoma

Question 9

MOT of Hepadnavirus

Answer 9

Blood

Question 10

Enumerate the viruses under the Family Herpesviridae

Answer 10

• Herpes simplex virus Type 1
• Herpes simplex virus Type 2
• Varicella-Zoster virus
• Cytomegalovirus
• Epstein-Barr virus
• Human herpesvirus 6
• Human herpesvirus 7
• Human herpesvirus 8

Question 11

Clinical syndrome caused by HSV-1

Answer 11

Mouth lesions

Question 12

Syndrome caused by HSV-2

Answer 12

Genital herpes

Question 13

Prominent feature of Herpesviruses

Answer 13

Latency

Question 14

Herpesvirus that causes mouth lesions

Answer 14

Herpes simplex virus type 1 (HSV-1)

Question 15

Herpesvirus that causes genital herpes

Answer 15

Herpes simplex virus type 2 (HSV-2)

Question 16

Syndromes caused by Varicella-Zoster virus (VZV)

Answer 16

Chickenpox

Shingles

Question 17

Stain used for Varicella-Zoster virus CPEs

Answer 17

Tzanck stain

Question 18

Seen in Tzanck stain for VZV CPEs

Answer 18

Giant cells

Question 19

Cytomegalovirus (CMV) can be isolated from

Answer 19

Blood
Urine
Throat

Question 20

Causes heterophile-negative mononucleosis

Answer 20

Cytomegalovirus (CMV)

Question 21

Uses shell vial culture for lab diagnosis

Answer 21

CMV

Question 22

Causes a heterophile-positive infectious mononucleosis

Answer 22

Epstein-Barr virus (EBV)

Question 23

Virus associated with Burkitt lymphoma and Hodkin disease

Answer 23

EBV

Question 24

Herpesvirus that can produce tumors

Answer 24

EBV

Question 25

Serologic diagnostic methods for EBV

Answer 25

- early antigen - viral capsid antigen: IgM and IgG - nuclear antigen

Question 26

Syndrome caused by Human herpesvirus 6 (HHV-6)

Answer 26

Exanthem subitum, AKA roseola/sixth disease

Question 27

Herpesvirus that causes a small percentage of roseola (5%)

Answer 27

Human herpesvirus 7 (HHV-7)

Question 28

Herpesvirus that is associated with Kaposi's sarcoma

Answer 28

Human herpesvirus-8 (HHV-8)

Question 29

DNA Virus that is the most common cause of cervical cancer

Answer 29

Human Papillomavirus (HPV)

Question 30

Viruses detected through molecular assays

Answer 30

HHV-6 HPV Parvoviruses

Question 31

Important viral species under Parvoviruses

Answer 31

Human parvovirus B-19

Question 32

Disease caused by human parvovirus B-19

Answer 32

Erythema infectiosum (fifth disease)

Question 33

Virus that causes erythema infectiosium (fifth disease)

Answer 33

Human parvovirus B-19

Question 34

Cells infected by parvovirus

Answer 34

Bone marrow ethrocytes

Question 35

Parvoviruses cause ___________ after infecting the erythrocytes in the bone marrow

Answer 35

Aplastic crisis

Question 36

Largest virus

Answer 36

Poxvirus

Question 37

Brick-shape virus

Answer 37

Poxvirus

Question 38

Disease caused by Poxvirus

Answer 38

Smallpox (variola)

Question 39

Vaccine against smallpox

Answer 39

Vaccinia

Question 40

Families of DNA viruses

Answer 40

``` Hepadnaviridae Herpesviridae Adenoviridae Papillomaviridae Parvoviridae Polyomaviridae Poxviridae ```