2- Neoplasia

Question 1

Example of Lymphatics Permeation ?

Answer 1

Breast carcinoma

Question 2

What is the steps of Invasion of Extracellular Matrix (ECM) ?

Answer 2

1- Detachment
2- Attachment
3- Degradation
4- Migration

Question 3

Metastasis is most common in ?

Answer 3

lymphatic & hematogenous (blood) spread.

Question 4

LYMPHATIC SPREAD It occurs more commonly with ?

Answer 4

Carcinomas

Question 5

Emboli drained by systemic veins are carried to ?

Answer 5

Right side of the heart

Question 6

Emboli drained by the Portal vein are carried to ?

Answer 6

liver causing liver metastases

Question 7

Spread occurs early by blood and rarely (10%) by lymphatics.

Answer 7

Sarcoma

Question 8

Spread occurs early by lymphatics then later by blood,

Answer 8

Carcinomas

Question 9

LYMPHATIC SPREAD It occurs more commonly with ?

Answer 9

Carcinomas

Question 10

What is the carcinomas spread relatively early by blood ?

Answer 10

carcinoma of thyroid, liver, kidney, prostate & placenta

Question 11

What is the The most common sites affected by metastases include ?

Answer 11

the liver, lungs, bones and brain.

Question 12

In the Transperitoneal spread the carcinoma of stomach, colon is ?

Answer 12

metastatic Peritoneal nodules

Question 13

In Transperitoneal spread In females, carcinoma of stomach, colon is ?

Answer 13

bilateral ovarian metastases (Krukenberg tumor)

Question 14

In females, carcinoma of stomach, colon leads to ?

Answer 14

bilateral ovarian metastases (Krukenberg tumor)

Question 15

Carcinoma in situ (CIS) represents a preinvasive stage of cancer and is characterized by severe or high grade epithelial dysplasia affecting whole thickness of epithelium without invasion of the basement membrane ?

Answer 15

CARCINOMA IN SITU

Question 16

What is the Fate of CARCINOMA IN SITU ?

Answer 16

Progression into invasive carcinoma

Question 17

Direct spread to a surface (skin or mucosa) leads to ulceration ?

Answer 17

malignant ulcer

Question 18

Direct spread from one hollow organ to another adjacent one causes a ?

Answer 18

malignant fistula

Question 19

Examples of locally malignant tumor ?

Answer 19

1- Basal cell carcinoma

2- Giant cell tumor of bone (osteoclastoma)

Question 20

Examples of locally malignant tumors ?

Answer 20

1- Basal cell carcinoma.

2- Giant cell tumor of bone (osteoclastoma).

Question 21

The most common sites affected by metastases include:

Answer 21

liver, lungs, bones and brain.

Question 22

What is the gross of Metastases ?

Answer 22

appear as scattered multiple round nodules

Question 23

Give example of Lymphatic Permeation ?

Answer 23

Breast carcinoma

Question 24

tumors of organs drained by the Portal vein are carried to ?

Answer 24

liver causing liver metastases