(2) Spinal Cord Flashcards
(121 cards)
1
Q
what system is the spinal cord a part of?
A
central nervous system
2
Q
where does the spinal cord continue form
A
the medulla oblongata (of the brainstem)
3
Q
sympathetic vs parasympathetic nervous system
A
sympathetic= fight or flight (spinal cord)
parasympathetic= rest and digest (brainstem/spinal cord)
4
Q
dorsal vs ventral spinal cord
A
dorsal/posterior= sensory INTO spinal cord
ventral/anterior= motor OUT OF spinal cord
5
Q
function of the foramen magnus
A
defines the border of the brainstem and spinal cord
- part of occipital bone
6
Q
4 main functions of the spinal cord
A
motor functions
reflex integration
autonomic functions
impulse conduction
7
Q
motor functions of the spinal cord
A
- enable us to move and interact with environment
- location of lower motor neurons controlling muscle function in limbs/torso
8
Q
reflex integration of the spinal cord
A
specific pathways originating from periphery allow for reflexive movements rather than those initiated by brain
(e.g. involuntary movement)
9
Q
autonomic functions of the spinal cord
A
sympathetic and part of the parasympathetic NS (ANS)
- internal organ function
10
Q
impulse conduction of the spinal cord
A
provides means of neural communication to and from the brain
- ascending tracts and descending tracts
11
Q
ascending vs descending tracts of the spinal cord
A
ascending= conduct impulses from peripheral sensory receptors to the brain
descending= conduct motor impulses from brain to muscles and glands
12
Q
where does the spinal cord start and end
A
start: foramen magnum
end: filum terminale
13
Q
2 enlargements of the spinal cord
A
cervical and lumbar enlargement
- contain network that control arm/leg movement
14
Q
cervical enlargement location
A
C5 – T1
controls arm movements
15
Q
lumbar enlargement location
A
L2 – S3
controls leg movements
- ends at conus medullaris
16
Q
central canal of the spinal cord function
A
filled with CSF
- nurtures spinal cord
- carries material
17
Q
dorsal and ventral roots pass through
A
dorsal= dorsal lateral sulcus
ventral= ventral lateral sulcus
18
Q
how many spinal cord segments?
A
31 in total
8- cervical 12- thoracic 5- lumbar 5- sacral 1- coccygeal
19
Q
where is dorsal root ganglia and what does it contain?
A
DRG is in the PNS
contains cell bodies of sensory neurons
20
Q
spinal cord segments give rise to ….
one exception
A
segments give rise to spinal nerves
exception: No C8 vertebrae
21
Q
cervical plexus and brachial plexus control what??
A
arm and neck movements
22
Q
dorsal rootlets enter where
A
enters posterolateral sulcus
- bears dorsal root ganglia (contain cell bodies of primary sensory neurons)
23
Q
ventral rootlets leave where?
A
leave from anterolateral sulcus
24
Q
what is a dermatome?
A
area of skin supplied by nerves from single spinal root
25
C1 and C3 segment dermatomes
C1 segment= no dermatome
C3= neck
26
does the face have a dermatome?
NO
face is innervated by cranial nerves (not spinal!)
27
spinal cord is located within... (why?)
vertebral canal
provides protection
28
3 protective sheets of the spinal cord are called?
Meninges
1) dura mater
2) Arachnoid mater
3) pia mater
29
dura, arachnoid and pia mater
dura= outer, toughest
arachnoid= middle, spiderweb
pia= inner, wrap spinal cord tissue
30
what is between the arachnoid and pia mater?
CSF
31
what goes between pia mater and dura mater?? (what is the function)
denticulate ligaments
- position spinal cord (centres it in meninge tube)
32
what segments does the spinal cord end?
L1/L2
33
how long is the spinal cord and vertebral column?
spinal cord= 42-45 cm
vertebral column= ~70 cm
34
caudal/lower end of the cord is anchored to...
end of dural tubal by filum terminal
35
structures at the end of the spinal cord
conus medullaris (L1)
lumbar cistern (L2)
filum terminale internum (L3)
dura mater (continues farther than spinal cord) -- (L4)
filum terminal externum (coccygeal ligament) -- (S2)
36
what and where is the cauda equina?
from L1/L2 --> S2
(above the filum terminale externum)
filled with dorsal and ventral roots
37
cauda equina is also called
horses tail
38
where to inject epidural needle? Why?
dural sac= filled with spinal nerves
able to insert needle without damaging spinal cord
(in lumbar region)
39
grey matter and white matter in spinal cord
grey= cell bodies of interneurons and motor neurons (surrounded by white matter)
white= heavy myelinated axons projecting too and form spinal cord (surrounds grey)
40
grey matter and white matter are divided into
grey= horns
white= funiculi
41
Lissauer's tract location and what does it contain
between substantia gelatinosa and surface of the cord
contains finely myelinated/unmylinated fibers
left side of body
42
at what levels is the posterior intermediate sulcus found
cervical and upper thoracic levels
43
anterior median fissure
extend almost to centre of cord
- at apex a thin zone of white matter (anterior white commissure) and thin grey matter zone separates central canal from subarachnoid space
44
posterior median sulcus
(less distinct)
glial septum extend from it all the way to grey matter surrounding central canal
45
location and function of substantia gelatinosa
distinctive region of grey matter, caps the posterior horns
- deals with finely myelinated and unmyelinated SENSORY fibres that carry PAIN and TEMPERATURE information
46
2 spinal reflexes
patellar (knee-jerk) reflex
flexor and crossed extensor reflex
47
patellar reflex
- cell body of afferent is in DRG
- tapping patellar tendon, stretches quadriceps
- quad muscle spindles excited and excite quad alpha motor neurons
- causing muscle to contract (completing reflex)
48
flexor and crosses extensor reflex
- initiated by cutaneous receptor
- involves whole limb
- caused by specific network in spinal cord
ex: withdrawal from pain stimuus
49
somatic nervous system afferents in the spinal cord
- what is the boss?
afferents and info from body goes INTO spinal cord
innervates muscles, causes contraction
Boss= cerebral cortex (generate decisions about how to move, what to do)
50
autonomic nervous system afferent fibers in spinal cord
- what is the boss?
ANS= control gut movements, heart, and internal organs (unaware)
```
afferent fibers (visceral= internal)- info goes into spinal cord through dorsal root
- innervate interneurons and motor neurons, and project to target organs (muscle/endocrine organs)
```
Boss= hypothalamus
51
general visceral sensory neurons monitor what 4 sensations in visceral organs
stretch
temperature
chemical changes
irritation
52
cell bodies of visceral sensory neurons are located where?
dorsal root ganglion
53
visceral pain
- no pain results when visceral organs are cut
- pain results from chemical irritation or inflammation
- often perceived to be of somatic origin (referred pain)
54
ex: gall bladder pain
visceral pain
- feel pain in arm, shoulder and stomach
55
where are sympathetic and parasympathetic preganglionic neurons segregated?
symp= thoracic and lumbar (intermediate horn)
para= brain stem and sacral
56
radicular vs medullary arteries
radicular= posterior/anterior, don't touch main arteries
- run dorsal and ventral spinal nerve roots
medullary= supply main arteries
57
3 major longitudinal arteries of the spinal crd
1 anterior spinal
2 posterior spinal arteries
- originate from vertebral arteries
- run length of cord
58
major longitudinal arteries are supplemented by:
segmental arteries
- derived from vertebral, deep cervical, intercostal and lumbar arteries
59
large radicular artery arises from.... and supplies what?
arises from intercostal artery on left between T9 and T11
- often supplies blood for lower spinal cord
60
6 veins in venous drainage
3 anterior
3 posterior spinal veins
61
venous drainage
- 3 anterior, 3 posterior spinal veins
- drained by medullary and radicular veins
- join internal vertebral venous plexuses in epidural space
62
3 types of nerve fibers in white matter of spinal cord
& where do they project to/from
1) long ascending fibers: project to thalamus, cerebellum or brainstem nuclei
2) long descending: project from cerebral cortex or from brainstem nuclei in grey matter
3) shorter propriospinal= interconnecting different spinal cord levels, mostly remain in propriospinal tract
63
what is the fasciculus proprius?
thick shell surrounding grey matter
| in white matter
64
where are the ascending and descending tracts in the spinal cord located
white matter
65
white matter is divided into 3 parts
posterior, lateral, anterior fasciculus
66
ascending tracts in spinal cord.. found... function
found in all 3 funiculi
bring info TO brain (Right side)
67
descending tracts in spinal cord... found... function
found primarily in lateral or anterior funiculi (not posterior)
- bring info TO BODY (left side)
68
are descending tracts sensory or motor?
MOTOR
69
are ascending tracts sensory or motor?
SENSORY
70
what do descending motor tracts represent
functional pathways that convey signals from brain to periphery/body
generate movement
71
name of descending motor tracts (all similar)
ends in spinal
72
cells of origin of descending motor tracts
cells of origin (upper motoneurons) are in cerebral cortex
- e.g lateral corticospinal tract
or in brainstem (e.g. rubrospinal tract)
- and innervate lower motoneurons in brainstem or spinal cord (final target)
73
descending motor tracts can be grouped into....
conscious (2) and subconscious tracts (4)
74
2 conscious motor tracts (descending)
lateral corticospinal tract
anterior corticospinal tract
-- used to consciously move something
75
4 subconscious motor tracts (descending)
vestibulospinal tract
tectospinal tract
reticulaspinal tract
rubrospinal tract
76
conscious descending tracts begin where?
both in primary motor cortex
| precentral gyrus
77
8 parts to the lateral corticospinal tract pathway
| descending, motor, conscious
1) fibers in cerebral cortex (precentral gyrus/motor cortex)
2) upper motor neuron descends through internal capsule
3) corticospinal tract
4) cerebral peduncle (midbrain)--- crux cerebri
5) basal pons
6) CROSS pyramids of medulla oblongata (cross to right)
7) lateral fasciculus
8) terminate in motor neurons in anterior horn (skeletal muscle) -- contraction occurs
78
8 parts to the anterior corticospinal tract pathway
| descending, motor, conscious
1) fibers in cerebral cortex (precentral gyrus/motor cortex)
2) upper motor neuron descends through internal capsule
3) corticospinal tract
4) cerebral peduncle (midbrain)--- crux cerebri
5) basal pons
6) medulla oblongata (white matter)
7) CROSS at final segments of spinal cord (anterior white commissure)
8) terminate in motor neurons in anterior/ventral horn (skeletal muscle) -- contraction occurs
79
anterior corticospinal tract important for
fine movement
80
corticospinal tracts are involved in
skilled motor activity, particularly in the limbs
81
cells of origin of corticospinal tracts
aka upper motor neurons
- they are pyramidal cells located in motor, premotor and supplemental motor cortices
82
upper motor neuron controls ...
lower motor neuron
83
if lose upper motor neuron then what happens?
don't lose all control because still have lower motor neurons
84
if lose lower motor neuron then what happens?
lose all control on muscles, cannot contract, lose tone, no reflex
85
upper vs lower motoneuron lesion effect on strength
upper lesion= decreased strength
lower lesion= decreased stength
86
upper vs lower motoneuron lesion effect on muscle tone**
upper lesion= increase tone*
lower lesion= decreased tone
87
upper vs lower motoneuron lesion effect on reflexes**
upper lesion= increased reflex*
lower lesion= decreased reflex
88
upper vs lower motoneuron lesion effect on atrophy**
- decrease in mass of muscle
upper lesion= mild atrophy
lower lesion= increased atrophy *
89
upper vs lower motoneuron lesion effect on other signs
upper lesion= clonus (large involuntary muscle contractions usually initiated by reflex)
lower lesion= fasciculations (small, spontaneous twitching)
90
what is brachial monoparesis
patient cannot move right arm
91
brachial monoparesis locations rule out
unlikely anywhere along corticospinal tract (internal capsule/brainstem)
- b/c the face and lower extremities would be involved
92
brachial monoparesis locatiosn ruled in
- arm area of primary motor cortex
| - or peripheral nerve supplying arm
93
brachial monoparesis common causes (3)
- infarct of a small cortical branch of middle cerebral artery
- compression injury
- diabetic neuropathy of the peripheral nerve
94
what is hemiparesis?
lost control of entire side of body
has control of face
95
hemiparesis locations ruled out (2)
- unlikely corticospinal tract below motor cortex, above the medulla because the corticobulbar fibers are nearby (face would be involved)
- unlikely peripheral nerve neuropathy (odd entire side is affected)
96
hemiparesis locations ruled in (2)
- arm and leg area of primary motor cortex
| - or corticospinal tract lower than the medulla
97
hemiparesis common causes (3)
- watershed infarct of the anterior cerebral artery
- medial medullary infarct
- compression of the cervical spinal cord
98
ascending sensory tracts represent
functional pathway that convey sensory information from periphery/body to brain
99
name of ascending sensory tracts (all similar)
begins with spino
100
ascending sensory tracts usually consist of ...
3 neurons
| - 1st, 2nd and 3rd order neurons
101
first order neurons of ascending sensory tracts are located...
always in dorsal root ganglia (DRG)
102
ascending sensory tracts can be grouped into (3)
conscious (2) and unconscious (2) tracts
103
2 ascending conscious tracts
posterior/dorsal column-medial lemniscus system
anterolateral system (spinothalamis tract)
104
3 ascending unconscious tracts
dorsal/posterior spinocerebellar tract
anterior/ventral spinocerebellar tract
cuneocerebellar tract
105
small and large diameter sensory fibers in the ascending conscious tracts
small= enter cord laterally, through Lissauer's tract
- terminating in substantia gelatinosa
large= enter through medial division of white matter, join posterior/dorsal columns
106
posterior/dorsal column medial lemniscus tract transmits what type of information (4)
proprioception ***
fine touch *
pressure
vibration
107
2 fasciculi in posterior/dorsal column-medial lemniscus pathway
fasciculus gracilis
fasciculis cuneatus
108
fasciculus gracilis vs cuneatus
gracilis= more lateral, transmit info coming from areas inferior to T6 segment
- lower limbs to brain (nucleus)
cuneatus= more medial, upper limbs to brain
109
damage to posterior/dorsal column-medial lemniscus pathway
- causes impairment of tactile perception
- results in ataxia (incoordination of movement)
- brain unable to direct motor activity properly without sensory feedback of position of limbs/body parts
110
10 parts to posterior/dorsal column-medial lemniscus pathway
| ascending, sensory, conscious
1) 1st order neuron (cell body DRG)
2) dorsal column spinal cord (Lissauer's tract)
3) fasciculis gracilis (lower) & cuneatus (upper) in spinal cord axons project to
4) medulla oblongata (reaches nucleus gracilis/cuneatus)
5) 2nd order neuron (cell body medulla oblongata)
6) axons CROSS as internal arcuate fibers in medial lemniscus (medulla)
7) project to thalamus, synapse with VPL nucleus
8) 3rd order neurons (cell bodies VPL nucleus)
9) internal capsule
10) project to somatosensory cortex (postcentral gyrus)
111
2 components of anterolateral/spinothalamic tract
| each responsible for
- crude touch, pressure, pain and temperature
lateral spinothalamic tract= crude touch, pressure
anterior spinothalamic tract= pain, temperature
112
10 parts to anterolateral/spinothalamic tract
| ascending, sensory, conscious
1) 1st order neurons (cell bodies DRG)
2) dorsal column spinal cord
3) branches ascend/descend via Lissauer's tract
4) synapse interneurons in substantia gelatinosa/nucleus proprius
5) CROSS via anterior white commissure in spinal cord
6) 2nd order neurons (cell bodies nucleus proprius)
7) spinal lemniscus
8) project to thalamus (VPL nucleus)
9) 3rd order neurons (cell bodies thalamus)
10) somatosensory cortex (postcentral gyrus)
113
anterolateral/spinothalamic tract reach out to PAG and spinoreticular trac
PAG--> provide natural analgesics (don't feel pain while panicking)
spinoreticular--> when pain info reaches tract, prepares us to react (inc heart beat, become anxious/nervous)
114
transverse cord lesion results in loss of
(lesion whole cord)
- vibration, position
- pain, temperature
- motor
LOWER BODY (waist down)
115
transverse cord lesion common causes (3)
- trauma
- tumors
- transverse myelitis (inflammation)
116
hemicord lesions results in loss of
(lose right side of spinal cord)
- lose control fine movement, fine touch/position on RIGHT side LOWER body
- lost pain info contralaterally, LEFT side LOWER body
117
hemicord lesion aka
brown-sequard syndrome
118
hemicord lesion common causes (2)
- penetrating injuries
| - lateral compression from tumors
119
posterior cord syndrome results in
- lose dorsal part of spinal cord
| - lose fine sensation of touch info (vibration and position) in WHOLE BODY, not face
120
posterior cord syndrome common causes (4)
- trauma
- tumors
- MS
- vitamin B12 deficiency tabes dorsalis (tertiary syphilis)
121
anterior cord syndrome results n
- lose ventral/lower part of spinal cord
| - lose pain/temperature and motor loss of muscles in WHOLE BODY, not face
