Flashcards in 2017 Physiology - Autonomic Nervous System Deck (30):
What are some of the purposes of the autonomic nervous system?
Controls visceral function
Coordinates responses to external stimuli
What pharmacological agent(s) is the Carniosacral division on the ANS related to/use?
What pharmacological agent(s) is the Thoracolumbar division on the ANS related to/use?
Which cranial nerves are Parasympathetic?
3, 7, 9, 10
Which nerve is responsible for parasympathetics below the neck?
CNX - Vagus
Which nerves (Pre or Post-ganglionic) are long/short in Parasympathetic nerves?
Pre = long
Post = short (often in the target organ)
What structure does the Sympathetic Outflow Tracts utilize?
Paravertebral sympathetic chain ganglia
Prevertebral sympathetic chain ganglia
Which organ can have direct Sympathetic innervation without a ganglia?
The Adrenal Medulla - chromaffin cells
What are the two types of receptors of the Parasympathetic system?
Nicotinic and Muscarinic
What are the two types of receptors of the Sympathetic system?
A1, M1, M3, M5 receptors share a common secondary messenger and G-proteins, what are they?
IP3, DAG to increase Ca++.
Gq receptor proteins
A2, M2, M4 receptors share a common secondary messenger and G-proteins, what are they?
Adenylate cyclase (inhibits) hence it inhibits cAMP
Gi receptor proteins
B receptors operate through which secondary messenger and G-protien?
Adenylate cyclase (activates) hence stimulates cAMP
Gs receptor proteins
What is the NT for ALL preganglionic neurons?
What is the NT for somatic motor neurons (alpha and gamma) aka. muscles?
What NT is used by Parasympathetic postganglionic neurons on the target organ?
Where is the sympathetic-cholerneric effect seen?
Sympathetic preganglionic to sweat glands
What is the principle adrenergic NT?
What NT is released by sympathetic postganglionic neurons?
What NT(s) is released by the Adrenal Medulla?
NE and Epi
Do the parasympathetic nerves stimulate anything outside of the viscera?
No, only the sympathetics do.
What type of receptor is on cell bodies of all postganglionic neurons in both symp and parasymp ganglia?
Nicotinic - Ng - N2
Parasympathetic: What type of receptor is on skeletal muscle?
Nm - N1
What type of receptor is on effector/target organs (glands, smooth muscle, cardiac muscle) except adrenal medulla?
Are alpha 1 receptors pre or post junctional or both?
Are alpha 2 receptors pre or post junctional or both?
What is tachyphlaxis?
Down regulation of a receptor based on the continued/overuse of a substance (or NT)
What are the functions of the Parasympathetic system? DEM BBLUESS
Defecation, emesis, miosis, bradycardia, bronchoconstriction, lacrimation, urination, erection, salivation, secretion
Which dominates (Para or Symp) if stimulated at the same time?