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2018 Flashcards

(35 cards)

1
Q

Ranitidine MOA

A

H2 blocker

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2
Q

Propranolol MOA

A

Non selective B1/B2 blocker

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3
Q

Chlorphenamine MOA

A

H1 blocker

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4
Q

Intron definition

A

Non coding section of an RNA transcript, spliced out before the RNA molecule is translated into a protein

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5
Q

Exon definition

A

A segment of a DNA or RNA molecule containing information coding for a protein

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6
Q

Haploid definition

A

Presence of a single set of chromosomes in an organism’s cells

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7
Q

Site of melatonin secretion

A

Pineal gland

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8
Q

Site of glucagon secretion

A

Alpha cells in the islet of langerhans

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9
Q

Site of calcitonin secretion

A

C cells (parafollicular)

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10
Q

Where do the coronary arteries arise from

A

Right cusp of the aortic valve, at the right aortic sinus

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11
Q

Vitamin needed for myelin and connective tissue

A

Vit A

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12
Q

Vit needed for absorption of calcium and phosphorus

A

Vit D

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13
Q

Vit found in bone and necessary for muscle contraction

A

Calcium

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14
Q

Cyanotic baby <24h old no murmur

A

TGA

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15
Q

Role of Hepcidin

A

Part of cytochrome, plays a role in iron metabolism

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16
Q

Absorption site of CSF

A

Arachnoid villi

17
Q

MOA of MMF

A

Inhibits inosine 5 monophosphate

18
Q

Gastric emptying by which nerve?

19
Q

How does Parvovirus B!9 cause anaemia

A

Cytotoxicity of progenitor cells

20
Q

Hormone deficient in diabetes insipidus

A

Growth hormone

21
Q

What is prolonged in haemorrhagic disease of the newborn

22
Q

Which Ca should be given irradiated blood

A

Hodgkin’s lymphoma

23
Q

Layer of skin affected by SSSS

A

Stratum granulosum

24
Q

Girl - unconscious, brother died of SIDS, IX - high ammonia, normal lactate, low glucose

25
Mechanism of omeprazole
Suppresses gastric acid secretion by specific inhibition of the H/K/ATPase enzyme system at the secretory surface of the gastric parietal cell
26
Mechanism of anaemia in coeliac disease
Coeliac disease can cause damage to the small intestine where iron, folate and Vit B12 are absorbed
27
Mechanism of salbutamol induced hypokalaemia
Na and H receptor
28
How to diagnose psychogenic Polydipsia
Water deprivation test
29
Spinal abnormalities in klippel fiel syndrome
Fusion of the cervical vertebral bodies
30
Reason to give high supplement of O2 in pneumothorax
Nitrogen washout
31
Dilatation of the 4th ventricle due to
Luschka and magendie obstruction
32
Baby with widening of the wrist and metabolic acidosis
Distal RTA
33
Congenital defect in DiGeorge
3rd and 4th pharyngeal arch
34
Syringomyelia at T6 what will be lost
Cough, posture and maintain balance
35
Listeria
Gram +ve rod