2024

Question 1

Cannabis used to treat what?

Answer 1

TMJ issues

Question 2

Which describes the volume of fluid in which a drug would need to be dissolved to have the same concentration in plasma?

Answer 2

Volume of Distribution

Question 3

Which describes the movement of a drug from its site of administration into the central compartment?

Answer 3

Absorption

Question 4

Bioavailability of IV:

Answer 4

100%

Question 5

Which organ has the highest amount of blood flow per mL/min/100gm?
a. Heart
b. Liver
c. Kidney
d. Brain

Answer 5

c. Kidney

Question 6

CO =

Answer 6

SV x HR

Question 7

Which Cytochrome P-450 system is most common?
a. CYP 2D6
b. CYP 2C9
c. CYP 3A4

Answer 7

c. CYP 3A4

Question 8

Loading Dose includes what in the equation?
a. Volume of distribution
b. Steady state concentration
c. Bioavailability
d. All the above

Answer 8

d. All the above

Question 9

How long does it usually take for a drug to be synthesized all the way until phase IV?
a. 8 years
b. 17 years

Answer 9

a. 8 years

Question 10

Predictable, dose related reaction not part of the desired therapeutic effect

Answer 10

Side effect

Question 11

Which improves burning mouth syndrome?

Answer 11

Alpha-lipoic acid

Question 12

evofloxacin is 2C9 inhibitor, warfarin is 2C9 substrate, what happens if taken together?

Answer 12

increased warfarin effect

Question 13

Results from covalent modification and alteration of DNA?

Answer 13

Mutagenesis

Question 14

Vaughn-Williams Classification for B-adrenoceptor blockers?

Answer 14

class II

Question 15

Superfamily of receptors bound to heat shock proteins in ctyoplasm of nucleus

Answer 15

Steroid receptors

Question 16

Which competitively inhibits conversion of plasminogen to plasmin by TPA?

Answer 16

Tranexamic acid

Question 17

Which drug is associated with anaphylactic shock?

Answer 17

penecillin

Question 18

Which dry secretions and increases hr in nerve agent exposure?

Answer 18

atropine

Question 19

Which regenerates Achesteras after nerve agents?

Answer 19

Pralidoxime

Question 20

Patient is using albuterol for asthma, which medication is most likely to result in pharmacodyamic interaction and negate use?

Answer 20

Propranolol

Question 21

Enzyme responsible for breaking down acetylcholine in serum

Answer 21

acetylcholinesterase

Question 22

Clot occurs in the veins and contains mostly fibrin?

Answer 22

Red thrombus

Question 23

Which should you avoid in asthma?
a. aspirin/nsaids
b. opiates and barbiturates
c. antihistamines
d. All the above

Answer 23

d. All the above

Question 24

Non-covalent type of interaction

Answer 24

formation of hydrogen peroxide

Question 25

Drug for chronic dry mouth, avoid adverse effects while max stimulation of saliva

Answer 25

M3 receptors

Question 26

Property of drug gives ability to bind to several subtypes of adrenergic receptors?

Answer 26

Multiple steroisomers

Question 27

In pregnancy have drug variation due to:

Answer 27

increased RBF and GFR

Question 28

Positive inotropic that increase gag reflex:

Answer 28

digoxin

Question 29

Colesevelam mechanism of action?

Answer 29

binding to bile acid and preventing resorption

Question 30

Difference between pharmacodynamic and pharmacokinetics?

Answer 30

Pharmacodynamic - drug on body and Pharmacokinetics - body on drug

Question 31

Movement of sodium with what phase of cardiac AP

Answer 31

Phase 0

Question 32

Sildenafil is a

Answer 32

Phosphodiesterase 5 inhibitor

Question 33

Catalyzes rate limiting step

Answer 33

Lovastatin

Question 34

Which is the last step in atherogenesis?

Answer 34

Fibrous cap

Question 35

Intracellular concentration key in smooth muscle tone

Answer 35

calcium

Question 36

Which organ is responsible for first pass?

Answer 36

liver

Question 37

Depolarizing paralytic

Answer 37

Succinylcholine

Question 38

Dose response curve when adding a competitive antagonist?

Answer 38

shifts right

Question 39

Inhibits COX1 preventing formation of thromboxane A?

Answer 39

Aspirin

Question 40

alpha -1 receptor:

Answer 40

increases sympathetic tone

Question 41

Which is the optimal level for HDL?

Answer 41

Greater than or equal to 60mg/dL

Question 42

The “good cholesterol”

Answer 42

HDL

Question 43

The “bad cholesterol”

Answer 43

LDL