Sketchy Pharm 100 Question Final Flashcards
(102 cards)
What is a common side effect (up to 10%) of ACE inhibitors due to the buildup of bradykinin?
a. Cough
b. Gingival hyperplasia
c. Gynecomastia
d. Hypotension
a. Cough
Which is a pure opioid antagonist that blocks opioid receptors and is used to reverse opioid overdoses
a. Gabapentin (Neurontin)
b. Fentanyl (Duragesic)
c. Naloxone (Narcan)
d. Tramadol (Ultram)
c. Naloxone (Narcan)
Ibuprofen is likely to cause a drug interaction with which of the following?
a. Acetaminophen (Tylenol)
b. Doxycycline (Doryx)
c. Warfarin (Coumadin)
d. Oxycodone
c. Warfarin (Coumadin)
RW is being treated for Generalized Tonic-Clonic Seizures with Valproic Acid (Depakote), Gabapentin (Neurontin), and topiramate (Topamax). In addition, RW is treated for Schizophrenia with Risperidone (Risperdal). Routine therapeutic lab monitoring reveals a drop in platelet level from 320,000 to ONE of the following? 160,000. The medication most likely to contribute to the development of a dose related thrombocytopenia is which
a. risperidone (Risperdal)
b. topiramate (Topamax)
c. gabapentin (Neurontin)
d. valproic acid (Depakote)
c. gabapentin (Neurontin)
SI is a 42 year old undergoing endodontic treatment for tooth number 15, which has irreversible pulpits and extremely percussion sensitive. He reports she has hypertension but is otherwise healthy. His blood pressure is currently well controlled. He reports the only medication he takes is amlodipine. He reports no known allergies. Which of the follow is the best pain management regimen?
a. Acetaminophen 325 mg, 2 tablets qid for 48-72 hours post procedure, then prn
b. Acetaminophen 300 mg with codeine 30 mg (Tylenol #3), 1-2 tablets gid for 48-72 hours post procedure, then prn
c. Ibuprofen 600 mg qid alternating with acetaminophen 650 mg gid or 48-72 hours post procedure, then prn
d. Oxycodone/acetaminophen 5/325 mg qid for 48-72 hours post procedure, then prn
file had no answer
i think it might be… c
In a patient who presents with severe cholinergic toxicity, which of the following symptoms would atropine NOT be effective in treating?
a. Paralysis
b. Hypersalivation
c. Bradycardia
d. Excessive urination
a. Paralysis
What are the most common side effects associated with selective serotonin reuptake inhibitor (SSRI) use?
a. sedation, weight gain
b. orthostatic hypotension, dizziness, tachycardia
c. blurred vision, dry mouth, constipation, urinary retention
d. nausea, vomiting, diarrhea, headache, insomnia
c. blurred vision, dry mouth, constipation, urinary retention
Calcium and Vitamin I supplementation is recommended for patients taking which ONE of the following antiepileptic medications?
a. valproie acid (Depakote)
b. levetiracetam (Keppra)
c. zonisamide (Zonegran)
d. tiagabine (Gabitril)
a. valproie acid (Depakote)
Which antianginal medication works by inhibiting the late inward sodium current (…) in ischemic myocardium?
a. Atenolol (Tenormin)
b. Isosorbide mononitrate (Imdur)
c. Ranolazine (Ranexa)
d. Verapamil (Calan/Verlan)
a. Atenolol (Tenormin)
hich of the following is an arrhythmia that results in heart rate less than 60 beats per minute?
a. Bradycardia
b. Delayed after-depolarization (DAD)
c. Tachycardia
d. Ventricular fibrillation
a. Bradycardia
hich antidepressant’s mechanism of action includes both serotonin and norepinephrine reuptake inhibition?
a. fluoxetine (Prozac)
b. bupropion (Welbutrin)
c. venlafaxine (Effexor)
d. citalopram (Celexa)
c. venlafaxine (Effexor)
hich medications possess analgesics and anti-inflammatory properties?
a. Acetaminophen
b. Naproxen
c. Oxycodone
d. Tramadol
a. Acetaminophen
hich medication increases cardiac contractility by inhibiting the phosphodiesterase-3 enzyme (PDE3)?
a. Digoxin (Lanoxin/Digitek)
b. DOBUTamine (Dobutrex)
c. Levosimendan (Simdax)
d. Milrinone (Primacor)
d. Milrinone (Primacor)
Nitric Oxide causes vasodilation by activating which of the following enzymes?
a. Adenylyl cyclase
b. Angiotensin converting enzyme
c. Guanyly cyclase
d. Phosphodiesterase 5
c. Guanyly cyclase
What herbal product is recommended in treatment guidelines for depression?
a. kava kava
b. turmeric
c. ginseng
d. St. John’s wort
file was confusing but I assume it is d
Which of the following antiepileptic medications is known to cause a significant amount of cognitive impairment and is associated with an increased risk of nephrolithiasis the patient is not adequately hydrated?
a. phenobarbital (Luminal)
b. phenytoin (Dilantin)
c. lamotrigine (Lamictal)
d. topiramate (Topamax
b. phenytoin (Dilantin)
Acetaminophen is contraindicated in which of the following conditions?
a. Active hepatitis
b. Acute heart failure
c. Asthma exacerbation
d. Recent gastric ulcer
a. Active hepatitis
Which of the following results from covalent modification and alteration of DNA?
a. teratogenicity
b. mutagenesis
c. carcinogenicity
d. cardiotoxicity
b. mutagenesis
Which of the following medications is used for management of chronic neuropathic pain and has been used for pre-operative and peri-operative analgesia in dental and other surgical procedures?
a. Aspirin
b. Celecoxib (Celebrex)
c. Duloxetine (Cymbalta)
d. Pregabalin (Lyrica)
file had no answer… but maybe it is d
Which of the following medications prevents the conversion of angiotensinogen to angiotensin I?
a. Aliskiren (Tekturna)
b. Captopril (Capoten)
c. Losartan (Cozaar)
d. Spironolactone (Aldactone)
a. Aliskiren (Tekturna)
Which of the following is a “depolarizing” neuromuscular blocker?
a. Vecuronium
b. Succinylcholine
c. Rocuronium
d. Methacholine
b. Succinylcholine
Which one of the of following medications is most likely to be associated with the development of anaphylactic shock?
a. Clozapine (Clozaril)
b. Valproic Acid (Depakote)
c. Sulfamethoxazole-Trimethoprim (Bactrim)
d. Penicillin (Pen-VK)
d. Penicillin (Pen-VK)
Patient AB is in your clinic today for a routine cleaning procedure and check-up. AB is 72 years of age and takes a multivitamin and a low dose of amitriptyline for neuropathic pain. After you complete your check for cavities and dismiss the patient, she attempts to rise out of the dental chair but immediately falls back into the chair, nearly falling to the ground. AB reports that she became extremely dizzy upon standing. A potential cause of this dizziness may be related to the amitriptyline and its ability to block alpha-1 receptors. This may result from what type of individual variation?
a. idiosyncratic
b. pharmacokinetic
c. pharmacodynamic
d. pharmacogenomics
c. pharmacodynamic