Pharmacokinetics/dynamics Flashcards
0
Q
Formula for half life
A
t1/2 = Vd x 0.7 / Cl
1
Q
Formula for maintenance dose
A
Maintenance dose = (target conc)(clearance)(dosing interval)/(bioavailability)
IV bioavailability = 1 and dosing interval = 1
2
Q
How many half-lives to reach steady state (or eliminate drug)?
A
4-5
3
Q
Loading dose formula
A
Loading dose = Vd x target conc / bioavailability
