UWorld Pharm Flashcards

0
Q

Adverse effects of protease inhibitors

A
  • Lipodystrophy: deposition of fat on back and abdomen, buffalo hump, central obesity and peripheral wasting
  • Hyperglycemia
  • p450 inhibition
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1
Q

Indinavir

A

Antiretroviral protease inhibitor. These drugs are always used as part of HAART, never alone

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2
Q

How is isoniazid metabolized?

A

Acetylation. Can be fast or slow acetylators.

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