UWorld Pharm Flashcards
0
Q
Adverse effects of protease inhibitors
A
- Lipodystrophy: deposition of fat on back and abdomen, buffalo hump, central obesity and peripheral wasting
- Hyperglycemia
- p450 inhibition
1
Q
Indinavir
A
Antiretroviral protease inhibitor. These drugs are always used as part of HAART, never alone
2
Q
How is isoniazid metabolized?
A
Acetylation. Can be fast or slow acetylators.