23 General Anesthesia II Flashcards Preview

2 Pharm Unit > 23 General Anesthesia II > Flashcards

Flashcards in 23 General Anesthesia II Deck (40):
1

Midazolam is what type of drug?

a benzodiazepine

2

Frequently Midazolam is given as a premedication for anesthesia because it has what effect?

It has an Anti-anxiety effect as well as an amnesia effect

3

What is an induction in anesthesia?

initiation of unconsiousness in preparation for intubation.

4

An induction agent is generally combined with what ?

a muscle relaxant

5

T/F Most induction agents enter the tissues, then go to the brain because it takes longer to cross the BBB?

False, they go to the brain first then disperse to the tissues.

6

During a surgery using general anesthesia, there is a "balanced" technique using 3 major drugs which are?

1) Volatile anesthetic
2) muscle relaxant
3) Opioid

7

T/F When the patient is emerging from general anesthesia, antagonistic drugs are given to help the person regain consciousness?

False, only when the patient is having difficulty waking up.

8

When do the side effects of the anesthetics diminish or abate?

during the recovery period

9

Which drug is considered the newest anestetic induction agent?

Propofol. This is the micheal jackson drug.

10

What is propofol dissolved in?

intralipid

11

T/F Propofol has a very little hangover effect?

TRUE

12

What do you give a person that has been overdosed with propofol?

Nothing. There is no antagonist for this drug. You can only maintain life support.

13

Can Propofol be used for induction, maintenance, or both?

Both

14

What is etomidate?

an intravenous induction agent

15

What does etomidate do to your breathing?

depresses it

16

what does etomidate do to your cardiovascular system?

Nothing, it does not depress it.

17

T/F Etomidate, propofol, ketamine, and barbituates do not have reversal agents (antagonists) in case of an overdose?

TRUE

18

Ketamine works on which receptors?

NMDA receptor (It's an antagonist)

19

T/F Ketamine depresses both the cardiovascular and respiratory systems?

False, it does not depress either one.

20

Ketamine is used as a_______ for general anesthesia?

induction agent

21

Ketamine produces which 3 effects?

sedation
amnesia
analgesia

22

T/F Ketamine is a phenylcyclidine derivative?

TRUE

23

Methohexital is considered to be a?

Oxybarbiturate

24

Thiopental is considered to be a?

Thiobarbiturate

25

Barbiturates are used for?

intravenous induction of general anesthesia

26

Do barbiturates act fast of slow?

Fast on the brain

27

How do barbiturates act of the respiratory drive?

they cause respiratory depression

28

T/F barbiturates are considered highly soluble lipids?

TRUE

29

How long does it take for you to recover from a barbiturate anesthetic?

5-8 min

30

why is the recovery from barbiturates so quick

It is due to the quick redistribution of the drug from the brain to other tissues

31

GABA receptors are considered?

Inhibitory

32

Midazolam, diazepam, and lorazipam are all types of which class of drug?

Benzodiazepines

33

Benzodiazapines are used as a premedication for general anesthesia because they cause?

sedation and amnesia

34

do bensodiazapines causes respiratory depression?

yes

35

Can you reverse (antagonize) a benzodiazepine?

Yes, you use flumazenil.

36

Morphine is a benchmark drug that is used as a?

analgesic

37

What does fentanyl do?

Its an opioid so it is used for analgesia

38

Is the drug fentanyl fast onset? lipid soluble? antagonizable?

1) very quick onset
2) lipid soluble
3) can be antagonized by naloxone

39

Fentanyl is generally used in anesthesia as a premedication but it can also have an effect on the MAC of anesthetics. What does it do with the MAC?

It decreases the MAC of volatile anesthetics.

40

What does fentanyl do to the blood pressure?

nothing really.