23: Great Vessel Development Flashcards
Where do aortic arches arise from? What are they located in?
Arise from aortic sac, are located in pharyngeal arches
Where do paired dorsal aortas fuse?
T4 level
What do intersegmental arteries run between and what forms them?
Run between somites, form from vasculogenesis
What forms parts 1-4 of the aortic arch?
1: aortic sac
2: AA IV
3: left dorsal aorta proximal to 7th intersegmental A
4. Left dorsal aorta distal to 7th intersegmental A
What does the remainder of the dorsal aorta form?
Descending/abdominal aorta
Vitelline arteries
Vessels that supply yolk sac and eventually GI tract
Umbilical artery path
Branch from dorsal aorta -> placenta + connect with developing bladder
What parts of the fetus receive the most oxygenated blood?
Heart, head, neck, UEs
Patent ductus arteriosus
DA remains at birth, connecting the aorta and pulmonary trunk -> blood circulated through lungs much more than through body, causing LV hypertrophy and pulmonary congestion
Risk factor for patent ductus arteriosus
Maternal rubella
Coarctation of the aorta
Narrowing/constrictions of the aortic lumen
Post vs preductal coarctation of the aorta
Either before or after the ductus arteriosus
Symptoms of aberrant origin of R subclavian and why they occur
Dysphagia and dyspnea bc R dorsal aorta must cross esophagus to reach RUE
Double aortic arch S/S
Esophageal dysfunction and strangulation of trachea bc aortas are wrapped around esophagus
Common cardiac anomaly in DiGeorge syndrome
Inerrupted aortic arch
