237 valvular Heart Disease Flashcards

(59 cards)

0
Q

Earliest xray changes in MS

A
  • straightening of upper left border of cardiac silhouette
  • prominence of main pulmo arteries
  • dilation of upper lobe pulmonary veins
  • posterior displacement of esophagus by enlarged LA
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1
Q

Resting mean pressure of LA when kerley b lines are present

A

20 mmHg

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2
Q

Cause of kerley b lines

A

Distention of interlibular septae and lymphatics with edema

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3
Q

Where kerley B lines are most prominent

A

Lower and mid-lung fields

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4
Q

Normal mitral valve area

A

4-6 cm

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6
Q

Hemodynamic hallmark of MS

A

Elevated left AV pressure gradient

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6
Q

Murmur louder during inspiration and diminished during forced expiration

A
Carvallo's sign in
Tricuspid regurgitation (pulmo HTN)
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7
Q

In Ms, the left atrial pressure required to maintain a normal cardiac output

A

25 mmHg

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8
Q

High pitched diastolic decrescendo blowing murmur along the left sternal border

A

Graham steell murmur of PR

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9
Q

Mitral valve disease and severe pulmonary hypertension murmur: resulting from dilation of pulmonary valve ring

A

Graham steell murmur of PR

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10
Q

Diff PR from AR

A

PR has a palpable p2 and nay increase with inspiration

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11
Q

Murmur softer with administration of amyl nitrite

A

Austin flint murmur

In severe AR

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12
Q

MR may result from abnormality in 5 functional components of mitral calve apparatus

A
Leaflets
Annulus
Chordae tendinae
Papillary muscles
Subsequent myocardium
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13
Q

Papillary muscle involved in acute MI, rupture of which results to MR

A

Posteromedial papillary muscle

Bec of singular blood supply

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14
Q

Target inR MR

A

2-3

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15
Q

ECG in MVP

A

Commonly normal,

Biphasic or inverted T waves in II, III, aVF

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16
Q

Duration of mVP midsystolic click

A

0.14 s

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17
Q

Barlow’s syndrome

Billowibg mitral leaflet syndrome

A

Mvp

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18
Q

Common age MvP

A

15-30 yrs

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19
Q

MC etiology of AS in adults

A

Degenerative calcification of aortic cusps

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20
Q

MC congenital heart valve defect

A

Bicuspid aortic valve

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21
Q

Mech dyspnea in AS

A

Elevated pulmo capillary pressure caused by elevations of LV diastolic pressures sec to reduced LV compliance

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22
Q

Three cardinal symptoms of aortic stenosis

A
  1. Dyspnea
  2. Angina pectoris
  3. Exertional syncope
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23
Q

When murmur of AS is transmitted downward to the apex where it can be confused with systolic murmur of MR

A

Gallavardin effect

24
Assoc with thrill or anacrotic shudder mc on left carotid
AS
25
Murmur of AS
Early systolic shortly after s1 ends before Aortic valve closure best heard at 2nd ICS right parasternal line
26
Mech for paradoxical splitting of s2
LV systole becomes so prolonged that AV valve closure now preceeds pulmonic valve closure
27
S4 in AS
Presence of Lv hypertrophy | Elevated LV end diastolic pressure
28
Valve area moderate AS
1-1.5 cm
29
Water hammer pulse/corrigan's pulse
AR
30
Alternate flushing a d paling of skin at root of nail while pressure is applied to the tip
Quinke's pulse (AR)
31
Pistol shot sound over the femoral arteries
Traubes sign of AR
32
To and fro murmur audible if femoral artery is lightly compressed with stethoscope
Duroziez sign
33
Murmur of AR
High pitched blowing decrescendo diastolic murmur heard beat at 3rd IcS left sternal border
34
Most characteristic auscultatory finding of MR
Systolic murmur of at least grade III/VI intensity
35
Major hemodynamic compensation for AR
Increase in LV end diastolic volume
36
Murmur of AR
Austin flint murmur
37
Auscultatory features augmented by sustained hand grip
AR
38
MS auscultation
Opening snap | Diastolic rumbling murmur
39
In Ms | Needed to exclude presence of L atrial thrombus prior to PMBV
TEE
40
Differential auscultate | MR vs MS
In MR OS and inc P2 absent S1 soft or absent S3 significant MR
41
Sign of recurrent systemic embolization/ severe pulmonary hypertension in MS
PAP > 50 mmHg rest | >60 with exercise
42
MR systolic murmur in | Ruptured chordae tendinae
Cooing or "sea gull" quality | Compared to flail leaflet Musical quality
43
Mitral regurgitation Diff Acute severe MR Versus chronic severe MR
Acute - v wave is prominent - decrescendo ends before s2 Chronic - v wave less prominent - holosystolic murmur
44
Patients with mild stenosis | Pmbv assess
Exercise Then yes if Pasp > 60 Pawp >= 25 MVG > 15
45
Rx MS
``` Symptom control - Beta blockers - Non DHP CCBs Rate control- digoxin Cardiovert if new onset AF Diuretics ``` Natl history - AF: warfarin - prophylaxis RF
46
Rx | Mitral regurgitation
``` Symptom control - diuretics for HF - vasodilators for acute MR Natural history - warfarin (AF) - vasodilators (HTN) ```
47
In MVP | IE prophylaxis indication
Only for pt with prior hx of IE
48
Indication for aspirin or warfarin in patients with MVP
Prevention of transient ischemic attack
49
Genetic polymorphisms libked to development of calcific AS
Vit D receptor Eatrogen receptor IL 10 Apo E4
50
Bicuspid aprtic valve defect
NOTCH1 gene
51
Why is there a prominent a wave in AS
Diminished distensibility of the RV cavity caused by the bulging hypertrophied IVS
52
Double apical impulse (palpable s4)
AS
54
Carotid arterial pulse is 2 systolic waves separated by a trough
Bisferiens | AR
55
Auscultatory features intensified by handgrip
AR | Increases systemic vascular resistance
55
Defines Ts
Diastolic pressure gradient bet RA and RV
56
2d echo characteristic finding of AR
Rapid high frequency diastolic fluttering of aNTERIOR mitral leaflet
57
Mean diastolic pressure gadient in TS required to elevated RA pressure
4 mmHg
58
PE | Anacrotic shudder heard over carotod arteries
AS