247 Hypertension Flashcards

(35 cards)

0
Q

Systolic hypertension with wide pulse pressure

A
FATH Arterial Pulse
Fever
AOrtic regurgitation
thyrotoxicosis
Hyperkinetic heart ayndrome

AV fistula
pDA

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1
Q

MC cause of death in hypertensive Pts

A

MI

Heart disease

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2
Q

Criteria HTN

A

Average of 2 or more seated BP readings during each or more of 2 outpatient visits

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3
Q

Night time BP in comparison to daytime BP

A

10-20% lower

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4
Q

Likelihood of hypertension among individuals greater than 60

A

65.4%

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5
Q

reduces risk of progressive heart failure and sudden cardiac death by 30%

A

Low dose spirinolactone

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6
Q

Measures arterial stiffness

A

Utz

Mri

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7
Q

Sec most freq cause of death in the world

A

Stroke

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8
Q

The strongest risk factor for stroke

A

Elevated BP

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9
Q

Map normal where CBg unachanged

A

50-150 mmHg

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10
Q

MC etiology of secondary hypertension

A

Primary renal dosease

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11
Q

Mech of kidney related ht

A

Diminaihed capacity to excrete Na
Excessive renib secretion
Sympathetic Ns overactivoty

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12
Q

Highbprotein excretion CKD

A

> 3g/day

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13
Q

Macroalbuminuria

A

Urine alv /crea ratio >300 mg/g

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14
Q

Microalbuminuria

A

30-300 mg/g

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15
Q

Classic sumptom of pad

A

Inermittent claudication

16
Q

Ankle brachial ratio diagnostic of PaD

A

50% stenosis in at least one major lower limb vessel

17
Q

CV risk increase for every 20 mmHg inc in syatolic and 10 mmHg inc in diastolic

A

Double CV risk

18
Q

Predominant cathecolamine secreted by pheochromocytoma

A

Epinephrine

And may present with hypotension

19
Q

Inherited pheochromocytomas

A

Von hippel lindau
Men2a
Men2b
Neurofibromatosis

20
Q

Gene mutations associated with paaganglioma syndromes

A

Succinate dehydrogenase enzyme genes

21
Q

Hypokalemia
Low renin
Low aldosterone

ENaC mutations

A

Liddle’s syndrome

22
Q

High renin patient

A

Vasoconstrictor form of hypertension

23
Q

Low renin (25% of HtN)

A

Volume dependent hypertension

24
Younger px more responsive
Beta blockers | aCEIs
25
Px over age 50 more respnaive to
Diuretics | Calcium antagonist
26
Direct renin inhibitor
Aliskerin
27
selective aldosterone antagonist
Eplerenone
28
Anti HTNs block V receptors and pwrioheral alpha adrenergic receptors
Carvedilol | Labetalol
29
Moa CCBs
Reduce vascular resitance through L channel blockade | Reduces intracellular calcium blunts vasocontriction
30
Accomplish trial
ACEi plus CCB (amlodipine) is superior to treatment with ACEI plus diuretic in reducing the risk of CV events and drath
31
After Stroke Treatment
Acei and diuretic
32
Pseudohypertension= sclerotic arteries how to Dx?
Osler maneuver | Occlude brachial artery by cuff
33
ANgiotensin receptor blocker moas
Selective blockade of AT1 receptors
34
Rx low renin HTN
Diuretics | Calcium agonists