248 Anomalies Of Aorta Flashcards

(17 cards)

0
Q

Mutation in gene that encode TGFB receptors and 2 (increased signaling cause aneurysm)

A

Loeys dietz syndrome

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1
Q

Anatomic remnant R aortic arch

A

Konmerell’s diverticulum

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2
Q

Mutations of type III procollagen

A

Ehlers danlos type IV

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3
Q

Most common pathologic lesion associated with degenerative aortic aneurysms

A

Atherosclerosis

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4
Q

Mechanism by which ACEI and ARBs reduce the rate of aortic dilatation

A

Block TGF beta

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5
Q

Size of ascending thoracic aneurysms for surgery

A

More than 5 cm

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6
Q

Risk of rupture aneurysms

A

5 cm 20-40

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7
Q

Repair size of abdominal aortic aneurysm

A

5.5 cm

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8
Q

Initial lesion syphilitic aortitis

A

Obliterative endarteritis of the vasa vasorum esp in adventitia

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9
Q

Predilection of mycotic aneurysms

A

Suprerenal abdominal aprta

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10
Q

Mc affected by syohilis

A

Proximal ascending aorta

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11
Q

Degeneration of collagen and elastic fibers in tunica media of aorta

A

Cystic medial necrosis

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12
Q

Mutated in marfan’s syndrome

A

Fibrillin 1 gene

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13
Q

Spondyloarthropathies aorta

A

Ascending aorta

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14
Q

Predilection traumatic aneurysm

A

Descending aortic aorta below ligamentum arteriosum

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15
Q

Most common pathology with ascending aortic aneurysms

A

Cystic medial necrosis

16
Q

Tx in aneurysm on marfans syndrome

Blocks tgf B signaling

A

ACEIs and ARBs