Squier Flashcards

1
Q

A cell’s capacity to give rise to ALL CELL types

A

pluripotency

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2
Q

A cell’s capacity to give rise to a SMALL NUMBER of different cell types

A

Multipotency

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3
Q

How can stem cells be used in diabetes?

A

Form differentiated beta cells in vitro and introduce through hepatic portal vein

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4
Q

How can stem cells be used in Parkinson’s?

A

Differentiate the stem cells into a neuron, graft into brain

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5
Q

How can stem cells be used in spinal repair?

A

Goal of demyelinating cells to treat spinal trauma

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6
Q

How are stem cells used in IVF?

A

Extra embryos are frozen and can be used to harvest ES cells

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7
Q

How are stem cells used in SCNT?

A

Early embryo can be used to create ES

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8
Q

How are induced pluripotent stem cells generated?

A

Engineered cells derived from somatic cells that resemble ES

Introducing foreign genes into cells using vector

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9
Q

How can stem cells be used in hematopoeitc stem cell transplantation?

A

Radiation preferentially kills diving cells, where hematopoeitc tissue of bone is most sensitive
Following repopulation from donor there is immune cell reprogramming and a transfer of tolerance

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10
Q

Vitamin C deficiency

A

Scurvy: swollen, spongy gums, anemia, muscle pain

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11
Q

Biotin

A

coenzyme for carboxylation rxns

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12
Q

Folic acid

A

transfers 1 carbon fragments in synth of amino acids

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13
Q

Vitamin B1

A

cofactor for enzymes; key to catalyzing bond cleavage

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14
Q

Vitamin B2 and B3

A

cofactor for oxidase and dehydrogenase enzymes

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15
Q

Vitamin B6

A

cofactor required for glycogen phosphorylase

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16
Q

Vitamin B12

A

cofactor for breakdown of odd-numbered fatty acids and mentioning synth

17
Q

Vitamin K

A

coagulation

18
Q

Vitamin A

A

important for vision, steroid hormones, reproduction and teeth

19
Q

Iodine

A

required for synth of thyroid hormones

20
Q

Zinc

A

structural or catalytic role like in cofactors for enzymes

21
Q

Copper

A

cofactors in enzymes that involve ox/redox

22
Q

Iron

A

oxygen transport
unbound iron is very toxic
transferred as transferrin
stored as ferritin

23
Q

Iron deficiency

A

leads to anemia and epithelial abnormalities

24
Q

Iodine deficiency

A

leads to goiter