Signaling pathway of steroid hormones

Question 1

Characteristic

Answer 1

Lipophilic, thus must circulate bound to specific binding globulins, which increases their solubility

Question 2

In men,

Answer 2

high SHBG lowers free testosterone => gynecomastia

Question 3

In women,

Answer 3

low SHBG raises free testosterone=> hirsutism

SHBG level increases during pregnancy