GU Flashcards
Urinalysis in UTI
what is pyuria?
> 10 WBC / mL
Urinalysis in UTI
nitrates show what from a sensitivity / specificity perspective?
very specific (-) but not sensitive (+)
shows true negatives
Urinalysis in UTI
esterase detection shows what from a sensitivity / specificity perspective?
very sensitive (+) but not specific (-)
shows true positives
Management of lower and upper UTI
most commonly used agents
TMP/SMX (Bactrim)
ciprofloxacin
amoxicillin clavulunate
Management of UTI in pregnancy
amoxicillin
nitrofurantoin (Macrobid)
increased duration, not dose
What is black box warning on ciprofloxacin?
Achilles tendon rupture
What is the cause of stress incontinence?
urethral incompetence
urine leakage from laughter, sneeze, exercise
What is the cause of urge incontinence?
detrussor overactivity - “overactive bladder”
urgency, involuntary urine loss, nocturia, frequency
Weight loss will benefit which type of incontinence?
urge
What class of medications is used for urge incontinence?
muscarinic receptor antagonists
What are examples of immediate release muscarinic receptor antagonists?
oxybutinin (Ditropan)
tolterodine (Detrol)
trospium (Sanctura)
What are examples of extended release muscarinic receptor antagonists?
darifenacin (Enablex)
Ditropan XL
Detrol LA
