Cartilage Flashcards

0
Q

Cartilage matrix is composed of

A

Glycoaminoglycans (GAGs), proteoglycans, collagen

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1
Q

How do chondrocytes receive nutrients?

A

Diffusion

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2
Q

What are the three types of cartilage?

A

Hyaline cartilage, elastic cartilage, fibrocartilage

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3
Q

Hyaline cartilage is composed of type __ collagen

A

Type 2

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4
Q

What functions does hyaline cartilage serve?

A

As articular (joint) cartilage, as the embryonic skeletal model, and endochondrial bone growth

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5
Q

What is elastic cartilage composed of?

A

Type 2 collagen and elastic fibers

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6
Q

Where is elastic cartilage found?

A

Epiglottis, larynx, external ear, Eustachian tubes

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7
Q

What is fibrocartilage primarily made of?

A

Type 1 collagen

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8
Q

What does fibrocartilage lack?

A

Perichondrium

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9
Q

Where is fibrocartilage found?

A

Pubic symphysis, intervertebral discs

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10
Q

Differentiating mesenchymal cells in developing hyaline cartilage aggregate to form

A

Chondrification centers

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11
Q

What cell type is responsible for the generation of the perichondrium?

A

Fibroblasts

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12
Q

The inner layer of the perichondrium is composed of

A

Chondrogenic cells

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13
Q

The outer layer of the perichondrium is composed of

A

Fibroblasts and type 1 collagen

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14
Q

What kind of CT is the perichondrium?

A

Dense irregular

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15
Q

Articular cartilage and fibrocartilage only expand via which method of growth?

A

Interstitial growth

16
Q

What do articular and fibrocartilage lack?

A

Perichondrium

17
Q

What kind of cartilage is articular cartilage?

A

Hyaline cartilage

18
Q

Where else does interstitial growth occur?

A

Early stages of hyaline cartilage formation and in the epiphyseal plates of long bones

19
Q

What shape are chondrogenic cells?

A

Spindly and narrow

20
Q

What are chondrogenic cells derived from?

A

Mesenchymal cells

21
Q

What can chondrogenic cells differentiate into?

A

Chondroblasts or osteoprogenitor cells

22
Q

What two cell types can differentiate into chondroblasts?

A

Mesenchyme and chondrogenic cells

23
Q

What do chondrocytes have an abundance of?

A

Free ribosomes