28 Flashcards
(19 cards)
Which of the following parameters can be abnormal in classic von Willebrand’s disease type I?
A. Bleeding time
B. PT
C. Platelet count
D. All of the above
A. Bleeding time
Platelet aggregation studies in cases of classic von Willebrand’s disease should reveal
A. normal platelet aggregation when factors such as ristocetin are used for testing
B. absence of aggregation when factors such as epinephrine are used for testing
C. decreased aggregation when factors such as ristocetin are used for testing
D. decreased ADP activity when tested
C. decreased aggregation when factors such as ristocetin are used for testing
The most common form of von Willebrand’s disease is
A. type I
B. type II
C. type III
D. all have about the same incidence
A. type I
Unique characteristic associated with a deficiency of factor XII deficiency is
A. frequent nosebleeds
B. no history of bleeding
C. a common factor deficiency
D. decreased risk of forming blood clots
B. no history of bleeding
Disseminated intravascular coagulation (DIC) can be initiated by
A. septic shock
B. severe sepsis
C. hemolytic RBC crisis
D. all of the above
D. all of the above
Laboratory results in acute DIC reflect abnormalities in which of the following coagulation components?
A. Platelet function
B. Excessive clotting and fibrinolysis
C. Accelerated thrombin formation
D. Fibrin formation
B. Excessive clotting and fibrinolysis
Primary fibrinolysis is characterized by
A. gross activation of the fibrinolytic mechanism
B. consumption of fibrinogen
C. consumption of coagulation factors
D. all of the above
D. all of the above
The hallmark of secondary fibrinolysis is the presence of
A. fibrin split products
B. fibrin degradation products
C. fibrin monomers
D. all of the above
D. all of the above
DIC is characterized by
A. microvascular thrombosis
B. fibrin deposition
C. active fibrinolysis
D. all of the above
D. all of the above
Which of the following factors can contribute to hypercoagulation?
A. Vascular endothelial damage
B. Increased blood flow
C. Decreased platelets
D. Decreased titers of clotting factors
A. Vascular endothelial damage
Antithrombin deficiency can cause a
A. primary hypercoagulable state
B. secondary hypercoagulable state
A. primary hypercoagulable state
Oral contraceptives can cause a
A. primary hypercoagulable state
B. secondary hypercoagulable state
B. secondary hypercoagulable state
Protein C deficiency can cause a
A. primary hypercoagulable state
B. secondary hypercoagulable state
A. primary hypercoagulable state
- Cancer can cause a
A. primary hypercoagulable state
B. secondary hypercoagulable state
B. secondary hypercoagulable state
- Pregnancy can cause a
A. primary hypercoagulable state
B. secondary hypercoagulable state
B. secondary hypercoagulable state
A characteristic of circulating anticoagulants is which of the following?
A. The most common specific factor inhibitor
B. Acquired inhibitors of clotting proteins
C. Also known as antiphospholipid or anticardiolipin
D. None of the above
B. Acquired inhibitors of clotting proteins
A characteristic of lupus anticoagulant is which of the following?
A. The most common specific factor inhibitor
B. Acquired inhibitors of clotting proteins
C. Also known as antiphospholipid or anticardiolipin
D. None of the above
C. Also known as antiphospholipid or anticardiolipin
A characteristic of factor VIII inhibitor is which of the following?
A. The most common specific factor inhibitor
B. Acquired inhibitors of clotting proteins
C. Also known as antiphospholipid or anticardiolipin
D. None of the above
A. The most common specific factor inhibitor
Warfarin is a vitamin ________ antagonist.
A. B
B. C
C. D
D. K
D. K
